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Bladder Preservation With Sacituzumab Govitecan + Zimberelimab for Muscle-Invasive Bladder Cancer in Cisplatin-unfit and Unwilling for Cystectomy Patients: Phase II Trial Patients with MIBC N0/N1 unwilling or unfit for cystectomy will receive SG + Zimberelimab for 3 cycles of treatment prior of ...
See “What is the most important information I should know about NERLYNX?” Liver problems.Changes in liver function tests are common with NERLYNX. Your healthcare provider should do blood tests before you begin treatment, monthly during the first 3 months, and then every 3 months as needed du...
To explore to what extent MNP-HC could be effective therapeutic agents, we analyzed their capability to interfere with drug resistance, as a stand-alone treatment or in combination with chemotherapy. To this purpose, we used two breast cancer cell lines both characterized by HER2 overexpression and...
OncLive®: What is the significance of the FDA approval of sacituzumab govitecan in patients with HR-positive, HER2-negative breast cancer? Traina: It is always significant when we have another highly effective agent FDA approved for our patients who are under ...
Provided by the Springer Nature SharedIt content-sharing initiative Subjects Cancer Immunology Oncology Sarcoma This article is cited by Developing CAR T-Cell Therapies for Pediatric Solid Tumors Gabriele Canciani Francesco Fabozzi Francesca del Bufalo ...
Discontinuation of HER2-targeted therapy is not recommended for patients who experience mild CTRCD, and it should be considered in patients who experience asymptomatic moderate CTRCD. More frequent cardiac monitoring should be accomplished in both cases [22] (Figure 1). Figure 1. An example of ...
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The final section discusses the future prospects of other anti-HER2 drugs, including lapatinib, trastuzumab emtansine, and pertuzumab, for the treatment of HER2-positive gastric cancer. The introduction of trastuzumab led to the establishment of a new disease entity, “HER2-positive gastric cancer,”...