[2]Miglietta F, Bottosso M, Griguolo G, et al. Major advancements in metastatic breast cancer treatment: when expanding options means prolonging survival. ESMO Open. 2022;7(2):100409. [3]Agostinetto E, Curigliano G, Piccart M. Emerging treatments in HER2-positive advanced breast cancer:...
Patients responding to one form of hormonal treatment had a greater likelihood of responding to subsequent hormonal manipulations. Additive hormonal therapy may provide effective palliation in males with advanced breast...
EP: 12.Treatment Options for HER2+, ER+ Metastatic Breast Cancer EP: 13.Evolving Treatment Landscape of HER2+ Metastatic Breast Cancer Vijayakrishna Gadi, MD, PhD: I’m going to go with that a little further. So Nancy, when you think about hormone-positive, HER2-positive disease, so maybe...
HER2-directed therapy: current treatment options for HER2-positive breast cancer Over the past decade, the management of HER2-positive breast cancer has evolved dramatically. In addition to advances in screening, genetic testing, imagin... S Ahmed,A Sami,J Xiang - 《Breast Cancer》 被引量: 74...
[2]Miglietta F, Bottosso M, Griguolo G, et al. Major advancements in metastatic breast cancer treatment: when expanding options means prolonging survival. ESMO Open. 2022;7(2):100409. [3]Agostinetto E, Curigliano G, Piccart M. Emerging...
A video from Virginia Borges (as part of University of Colorado Cancer Center), posted on Apr 14, 2023.
在中国,乳腺癌已成为女性恶性肿瘤中的头号杀手,而超过 90% 的女性在首次诊断时处于疾病早期 [1] 。在早期乳腺癌患者中,HR+/HER2-型占据了绝大多数。在早期 HR+/HER2-乳腺癌的治疗中,辅助内分泌治疗已经显著改善了患者的预后,并提高了他们的生存率。尽管取得了这样的进展,大约 20% 至 30% 的早期乳腺癌患者...
Human epidermal growth factor receptor 2 (HER2) positive breast cancer accounts for 20–25% of all breast cancers. Multiple HER2-targeted therapies have been developed over the last few years, including the tyrosine kinase inhibitors (TKI) lapatinib, neratinib, tucatinib, and pyrotinib. These drug...
The long-sought discovery of HER2 as an actionable and highly sensitive therapeutic target was a major breakthrough for the treatment of highly aggressive HER2-positive breast cancer, leading to approval of the first HER2-targeted drug — the monoclonal antibody trastuzumab — almost 25 years ago....
2. Saini KS, et al. Beyond trastuzumab: new treatment options for HER2-positive breast cancer. Breast. 2011;20(Suppl 3):S20–7. 3. Capelan M, et al. Pertuzumab: new hope for patients with HER2-positive breast cancer. Ann Oncol. 2013;24(2):273–82. ...