Most HER-2-positive breast cancer patients are deemed to be at a high risk of relapse by current treatment guidelines and thus, nearly all patients are allocated to (neo)adjuvant trastuzumab and chemo- therapy. According to the National Comprehensive Cancer Network (2009) practise guidelines in ...
Sibley, Jude
关键词: 曲妥珠单抗;HER-2 阳性晚期胃癌;化疗;分区生存模型;成本-效果分析 中图分类号:R979.1 文献标志码:A 文章编号: 1674-6376(2023)06-1286-07 DOI:10.7501/j.issn.1674-6376.2023.06.016 Cost-effectiveness analysis of trastuzumab combined with chemotherapy in treatment of HER-2 positive advanced ...
Discussion Histologic response to chemotherapy is currently the strongest prognostic factor in high-grade osteo- sarcoma, but it can only be assessed after several weeks of therapy.1 Thus, detection of chemosensi- tivity at the time of diagnosis would be of great clinical importance, but reliable...
“You have pretty good outcomes,” she said. “Not the same as private insurance, but a whole lot closer than what happens if you don’t have insurance at all or if you get Medicaid insurance after diagnosis.” A person has to make less than 250% of the...
A predictive model of pathologic response based on tumor cellularity and tumor-infiltrating lymphocytes (CelTIL) in HER2-positive breast cancer treated with chemo-free dual HER2 blockade Ann Oncol, 29 (1) (2018), pp. 170-177 View PDFView articleGoogle Scholar 48 A. Prat, C. Falato, L. ...
HER-2阳性乳腺癌治疗的进展 江苏省肿瘤医院 肿瘤内科 Her-2 检测的进展 肿瘤学临床实践指南 (NCCN指南®):乳腺癌。 版本1.2021。 2021年1月15日。 可在:www.NCCN.org。 于2021年1月 22日查阅。 HER2测试指南更新:2018年 ▪ 2018年对ASCO/CAP准则的更新认可了2013年准则,同时解决了悬而 未决的问题: ...
Pertuzumab (Perjeta®)(Genentech, Inc., EEUU) HER2 HER2-positive breast cancer [52] Abbreviations: TKIs, tyrosine kinase inhibitors; MAbs, monoclonal antibodies; NSCLC, non–small cell lung cancer; CRC, colorectal cancer; RET, rearranged during transfection tyrosine kinase; wt, wild type. Additio...
Many years ago, a friend of a friend was diagnosed with stage 2 breast cancer. She suffered through many rounds of brutal surgeries, chemo and radiation treatments. She had some brief periods of remission, but the cancer always came back. Her toughness, positive attitude, and love for Jesus...
Gilbert et al., “Targeted prodrug treatment of HER-2-positive breast tumor cells using trastuzumab and paclitaxel linked by A-Z-CINN™ Linker,” Journal of Experimental Therapeutics and Oncology 3(1):27-35, Jan.-Feb. 2003. Gillogly et al., “Ii-Key/HER-2/neu MHC class-II antigenic...