Public health Hepcidin-induced iron deficiency of obesity UNIVERSITY OF ILLINOIS AT CHICAGOHEALTH SCIENCES CENTER Carol Braunschweig TussingLisaObesity is associated with inflammation and low iron status. Hepcidin, a key iron-regulatory hormone, controls systemic iron metabolism by regulating the iron ...
Iron Deficiency: Impaired Liver Growth and DNA Synthesis in the Rat S ummary . This study deals with liver growth and DNA synthesis in young, rapidly growing rats weaned to an iron deficient diet. Shortly after the development of anaemia there was a depression in the rate of liver growth th...
Iron overload Iron deficiency Anemia 1. Introduction In the last decade, molecular understanding of systemic iron regulation greatly expanded on the physiological analysis of these processes worked out in the preceding fifty years. This review is focused on the iron regulatory hormone hepcidin and its...
Hepcidin in elderly Ecuadorians: A link between inflammation, BMI, and iron statusIron (Fe) deficiency is prevalent among obese & elderly individuals. Hepcidin (HC), the main regulator of Fe homeostasis, is important to this relationship. Low-grade chronic inflammation present in obesity up-...
Iron Deficiency and Raised Hepcidin in Idiopathic Pulmonary Arterial Hypertensiondoi:10.1016/j.jacc.2011.02.057hepcidiniron deficiencypulmonary hypertensionsoluble transferrin receptorObjectives This study sought to understand the prevalence and clinical relevance of iron deficiency in patients with idiopathic ...
discovery of hepcidin (the master regulator of iron metabolism) has shed new light on the regulation of iron homeostasis and has helped our understanding of complex clinical situations, such as those observed in critically ill patients, where several regulatory circuits interfere with iron metabolism ...
The understanding of iron metabolism in humans, especially of its mechanism involved in controlling iron absorption in the proximal small intestine, is of great importance since diseases associated with iron deficiency or overload are very common worldwide. Recent study on hepcidin which is senthesize...
Obesity modulate serum hepcidin and treatment outcome of iron deficiency anemia in children: A case control study Recently, hepcidin expression in adipose tissue has been described and shown to be increased in patients with severe obesity. We tried to assess the effect... M Sanad,M Osman,A ...
Hepcidinis a smallpeptide hormonemainly produced in the liver, and has a role in iron homeostastis.Hepcidinis upregulated in response to high iron levels and inflammation, and decreases duringanemiaandiron deficiency.Proteomicevaluation by surface-enhanced laser desorption-ionization time-of-flight mass...
Iron supplementation to treat anemia in patients with chronic kidney disease. Iron deficiency is prevalent in patients with chronic kidney disease (CKD), and use of oral and intravenous iron in patients with CKD who do not require di... A Besarab,DW Coyne - 《Nature Reviews Nephrology》 被...