The effectiveness of the hepatitis E vaccine in high-risk groups, such as chronic hepatitis B (CHB) patients, remains understudied. A key clinical manifestation of CHB is the persistent positivity of hepatitis B
Cost- effectiveness analyses of hepatitis A vaccine: a systematic review to explore the effect of methodological quality on the economic attractiveness of vaccination strategies. Pharmacoeconomics 2008;26(1):17-32.Anonychuk AM, Tricco AC, Bauch CT, Pham B, Gilca V, Duval B, et al. Cost- ...
Immunogenicity, effectiveness and safety of combined hepatitis A and B vaccine: a systematic literature review [ J]. Expert Rev Vac- cines, 2016,7 : 1-23. [ Epub ahead of print].Czeschinski PA, Binding N, Witting U. Hepatitis A and hepatitis B vaccinations: immunogenicity of combined ...
In healthy adults >95% of those vaccinated with hepatitis A vaccines have protective antibody titers at 20 years after follow-up.124,125 Vaccine immunogenicity may be lower in those with chronic liver disease and immunosuppression. Persons with chronic hepatitis B/C infection or those with other ...
Lastly, the effectiveness of a vaccine is commonly associated with the generation of specific immune responses, either T cell responses, both CD4 + and CD8 + peptide-specific, or antibodies against the vaccine’s antigen. In this context, we first evaluated the frequencies of HCV peptid...
Cost-effectiveness analysis of the universal use of hepatitis a vaccine in patients with chronic hepatitis Crupture of the spleenacute pancreatitischronic pancreatitissplenectomypancreatectomyBackground: Accessory spleen is a common congenital anomaly. There are currently no endoscopic ultrasound (EUS) ...
Although an HCV vaccine is not on the horizon yet, in 2016, the WHO proclaimed the ambitious goal to reduce new HCV infections by 90% by 2030, with the ultimate goal of HCV elimination6. The history of HCV research reads like a role model for successful biomedical and translational research...
AG Mulley,MD Silverstein,JL Dienstag - 《New England Journal of Medicine》 被引量: 447发表: 1982年 Indications for Use of Hepatitis B Vaccine, Based on Cost-Effectiveness Analysis To formulate indications for the use of hepatitis B vaccine, we examined the cost effectiveness of three strategies...
Hepatitis B virus (HBV), a member of the Hepadnaviridae family, is an enveloped virus that contains a circular partially double-stranded DNA genome that is 3.2 kb in length. The small genome consists of four overlapping reading frames.1,2 Because the presence of HBV is necessary for infectio...
Hepatitis C virus(HCV) infection is a prominent cause of chronic hepatitis,liver cirrhosis, andhepatocellular carcinoma(HCC), with up to 185 million chronically infected individuals worldwide, most of whom are undiagnosed and untreated.1,2A protective vaccine is not available, and those who clear ...