The anti-HBs titer at 24 weeks correlated positively with the proportions of plasma, Th1, Th2, and Tfh cells in the peripheral blood (Fig. 5B). The correlation between Th1 and Th2 cells was statistically significant (r-values of 0.488 and 0.458, respectively; p-values of 0.022 and 0.019...
The introduction of Ausria-125 was the beginning of an impressive development in virus diagnostics; however the test had one major disadvantage: the radioactivity caused significant difficulties in the normal diagnostic laboratory. It was therefore a big step forward when it became possible to label ...
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The introduction of Ausria-125 was the beginning of an impressive development in virus diagnostics; however the test had one major disadvantage: the radioactivity caused significant difficulties in the normal diagnostic laboratory. It was therefore a big step forward when it became possible to label ...
High-titer HBV was produced as we have previously described11. Briefly, HBV-containing supernatant from HepAD38 cells was collected every 3–4 days. Purification of HBV was performed via heparin affinity chromatography followed by sucrose gradient ultracentrifugation. HBV stocks were titered by HBV ...
HBsAb ≥100 mIU/mL was defined as an effective response (normal response), 10~100 mIU/mL was a low response, <10 mIU/mL meant without any response.16 After the whole course of immunization, the average titer of HBsAb was the highest in the 7–11 months old infants, representing the pe...
Table 3 Results of HBV-DNA titer measurement in culture medium of ICC derived organoids from three HBV (+) cases and three HBV (−) cases Full size table Fig. 7 The result of PCR electrophoresis shown that HBV-DNA was present in the supernatant of 3 HBV ( +) ICC derived organoid...
Hepatitis B immune globulin (HBIG), obtained by plasmapheresis of subjects with a high titer of anti-HBs antibodies, is effective for the post-exposure prophylaxis of hepatitis B when given in the first 48 hours after exposure, for example, in unvaccinated individuals who have been recently expo...
and 30% of dogs and cats in the United States are seropositive. A positive IgM titer or a fourfold increase in IgG or IgA titer can verify a recent infection; positive IgM titers can persist for months after infection, however, and high IgG titers have been detected 6 years after...
The present invention makes it possible to efficiently proliferate a hepatitis virus in vitro at a high infectivity titer with long-term stability by infecting, with the hepatitis virus, cultured cells packed into a lumen of a hollow fiber made of a permeabilized membrane. Furthermore, the present...