Test FAQ with the title Hepatitis C Viral RNA Genotype LiPA Question 1. Which hepatitis C virus (HCV) genotypes may be reported with the HCV RNA genotype line probe assay (LiPA)? The HCV LiPA genotype assay can detect all 6 major HCV genotypes (1–6)
et al. Applicability of Hepatitis C virus RNA viral load thresholds for 8-week treatments in patients with chronic hepatitis C virus genotype 1 infection. Clin. Infect. Dis. 62, 1228–1234 (2016). Article CAS PubMed Google Scholar Terrault, N. A. et al. Effectiveness of ledipasvir-...
Kunkel J, Ahmad A, Levi M, Reintjes R, Veldhuijzen, Foster G. Screening for viral hepatitis among migrants in the EU- The quest for "good screening practice". Annual Meeting of the European Association for the Study of the Liver, Amster- dam 2013. J Hepatol 2013; 58: A2281...
Given that screening for viral hepatitis in migrants will reduce morbidity, mortality and onward transmission of chronic viral hepatitis, the outstanding question is how should this be done?Aim: The aim of this observational study was to... H Lewis,K Burke,S Begum,... - Gut 被引量: 5发表...
Compound 3 time-dependently reduced HCV viral load over four weeks, with no apparent toxicity, in three out of four mice tested [164]. These CCZ derivatives are promising candidates for development as HCV therapies, for example in combination with existing DAA therapies, with potential benefits ...
HCV genotype was determined by LIPA (Quest Diagnostic, San Juan Capistrano, CA, USA) and HCV viral load was measured by PCR Quant (Amplicor HCV 2.0 PCR test system of Quest Diagnostic, San Juan Capistrano, CA, USA). Results were expressed as log10 IU/mL. Abdominal ultrasonography with ...
Tseng, T. C. et al. Serum hepatitis B core-related antigen level stratifies risk of disease progression in chronic hepatitis B patients with intermediate viral load.Aliment. Pharmacol. Therapeut.53, 908–918 (2021). CASGoogle Scholar
A true cure of HBV infection may not be feasible because HBV DNA is in the nucleus as the episomal form of cccDNA and integrated into the host genome producing HBsAg. Even among persons who have recovered from acute HBV infection, viral covalently closed circular DNA (cccDNA) can still be ...
viral replication and infectivity associated with a high HBV DNA load. Quantitative HBeAg testing can be a cost-effective alternative to the expensive HBV DNA viral load test, which currently can only be performed in a central laboratory. Quantitative and serial measurements of HBsAg and HBeAg ...
Even the most optimal treatment regimen today (combination of pegylated interferon-alfa with ribavirin and with extension of the therapy based on genotype and viral load) results in severe side effects (about 10% of patients have to discontinue because of side effects, and overall about 25% of ...