Hepatitis C virus–related mortality was classified using the ICD-10 code for acute viral hepatitis C (B17.1) or chronic viral hepatitis C (B18.2) as an underlying or multiple cause of death (n = 261 858). We earlier demonstrated that although HCV is underreported on death certificate...
Of 32 patients with non-A, non-B hepatitis, 10 (31%) were still anti-HCV-positive 12.8 years after the acute phase of the disease. Seven of the patients (21.9%) still had elevated ALT levels, and among these, 5 out of 5 patients who had been subject to parenteral risk were anti-...
Participants were included if they had a positive HIV antibody test (ELISA, confirmed by Western blot), had two or more affirmative responses to the CAGE (Cut down, Annoyed, Guilty, and Eye opener) alcohol screening questionnaire [10] or by physician-investigator diagnosis of alcoholism, spoke...
Patients with positive HCV antibody with unknown HCV RNA status were included because laboratory studies may have been completed outside the VHA or barriers to confirmatory HCV RNA testing may have existed. The index date was the date of the first outpatient visit or first positive HCV RNA and/...
After electrophoresis, the separated proteins were transferred onto a nitrocellulose membrane (Bio-Rad, Hercules, CA), blocked with 10% milk for 1 h, and incubated with the primary antibody overnight at 4 °C. The secondary antibody used was a 1:2000 dilution of HRP-linked anti-IgG. ...
A confirmed acute HepA case was defined as a probable case of acute HepA presenting a positive result for immunoglobulin M (IgM) for HepA virus. All probable HepA cases were assessed for acute HepA infection using microparticle enzyme immunoassay (MEIA) to detect the presence of anti-HepA virus...
Hepatitis C virus (HCV) infection and chronic kidney disease (CKD) have high prevalences in Taiwan and worldwide, but the role of HCV infection in causing CKD remains uncertain. This cohort study aimed to explore this association. This nationwide cohort
Geometric mean titers of anti-HAV antibody in the positive age groups were approximately 6,000 mIU/ml. The seropositives among older population were ascribed to the infections more than 40 years ago and the high anti-HAV titers have been maintained since that time. In Japan, people younger ...
antibody and PCR tests in the laboratory surveillance dataset, the study would have included some individuals without an active infection. For example, a study conducted in GP practices in Southwest England found only 40% of participants recorded as antibody positive were confirmed to be vireamic [...
2a). The percentage of NS5A-EGFP-positive cells did not change upon siCIDEB, siCD81, or siApoE treatment, suggesting that HCV reinfection did not happen in HCV-Jc1EGFP persistently infected cells (Fig. 2c). In addition, similar to siApoE, siCIDEB markedly decreased extracellular and ...