Hepatitis C virus (HCV) and hepatocellular carcinoma (HCC)doi:10.1016/0168-8278(91)91703-JG. Zala and J. Havelka and H.J. Joller-Jemelka and J.A. Garson and B. Risti and B. Meier and M. Schmid and H BühlerJournal of Hepatology...
Hepatocellular carcinoma (HCC) is one of the most common malignant tumors in the world. The incidence of HCC varies considerably with the geographic area because of differences in the major causative factors. Chronic hepatitis B and C, mostly in the cirrhotic stage, are responsible for the great...
The infection with the hepatitis C virus (HCV) is an example of the translational research success. The reciprocal interactions between clinicians and scientists have allowed in 30 years the initiation of empirical treatments by interferon, the discovery
Hepatitis C virus(HCV) infection is a prominent cause of chronic hepatitis,liver cirrhosis, andhepatocellular carcinoma(HCC), with up to 185 million chronically infected individuals worldwide, most of whom are undiagnosed and untreated.1,2A protective vaccine is not available, and those who clear ...
Consequently, HCV infection often causes extensive fibrosis, cirrhosis, and hepatocellular carcinoma (HCC)3. HCV, a member of the Flaviviridae family, is a positive-sense, single-stranded RNA virus. The 9.6-kb HCV genome encodes a long precursor polyprotein, which is sequentially processed into 3...
Children with CHC are generally asymptomatic, but long-term infection may lead to cirrhosis and HCC over time, and it is recognized that the degree of hepatic fibrosis correlates with age and duration of infection.3The benefits of treating children with CHC include prevention of disease progression...
most of these tumors contain HCV genomes classified as 1b.63Viral multiplication is sustained throughout the long-term course of chronic HCV infection and the development of cirrhosis and HCC. HCV genomes persist in tumor cells and can replicate, albeit at a lower rate than in non-tumoral live...
Finding these patients as early as possible can increase the screening of high-risk groups, so as to achieve early detection of HCC. A similar screening strategy launched in Japan, which screened people over the age of 40 for hepatitis B and C, achieved early detection in more than 60% of...
Blocking of G1/S transition and cell death in the regenerating liver of Hepatitis B virus X protein transgenic mice The Hepatitis B virus X (HBx) protein has been strongly implicated in the carcinogenesis of hepatocellular carcinoma (HCC). However, effects of the HBx pro... BK Wu,CC Li,HJ...
Successful prophylaxis of hepatitis C viral (HCV) re-infection and recurrent multiple hepatocellular carcinoma (HCC) after living donor liver transplantation (LDLT) with interferon beta and donor specific transfusion: Takafumi Ichida, Yoshinobu Sato, Hisami Watanabe, Satoshi Yamamoto, Satoshi Sugahara, ...