treatmentinterferon alphalamivudineHepatitis B virus (HBV) is a major world health problem and a common cause of cirrhosis and hepatocellular carcinoma. The natural history of HBV varies with many factors, including age of acquisition. Persistent elevation of alanine aminotransferase (ALT) levels and ...
Additionally, at present, the use of proprietary Chinese medicines in the market for the treatment of hepatitis B is mainly formula. For example, Dahuang zhechong formula, containing 12 kinds of traditional Chinese medicine ingredients such as cooked Rhubarb, white peony and rehmannia glutinosa, ...
Clinical application of estimating hepatitis B virus quasispecies complexity by massive sequencing: correlation between natural evolution and on-treatment evolution. PLoS One 9, e112306 (2014). PubMed PubMed Central Google Scholar Charuworn, P. et al. Baseline interpatient hepatitis B viral ...
Here we report on the development and comprehensive evaluations of an mRNA vaccine for chronic hepatitis B (CHB) treatment. In two different HBV carrier mouse models generated by viral vector-mediated HBV transfection (pAAV-HBV1.2 and rAAV8-HBV1.3), this
The focus of hepatitis Bvaccinationin pregnancy is to prevent vertical transmission from a mother withchronic hepatitis Binfection to hernewborninfant. However, a Cochrane review did not identify anyrandomised controlled trialsassessing hepatitis B vaccine compared with placebo or no treatment during preg...
Kim BK, Revill PA, Ahn SH. HBV genotypes: relevance to natural history, pathogenesis and treatment of chronic hepatitis B. Antiviral therapy. 2011:16(8):1169-86. doi: 10.3851/IMP1982. Epub[PubMed PMID: 22155900] [12] Luo A, Jiang X, Ren H. Entecavir-based combination therapies for ch...
- 《Annals of Internal Medicine》 被引量: 904发表: 2007年 Adefovir Dipivoxil for the Treatment of Hepatitis B e Antigen–Positive Chronic Hepatitis B Background: In preclinical and phase 2 studies, adefovir dipivoxil demonstrated potent activity against hepatitis B virus (HBV), including lamivudine...
Acute hepatitis B typically resolves on its own and may not require treatment (Liaw 2009). The goal of chronic hepatitis B treatment is to suppress HBV viral replication, which may limit hepatitis progression and may lower the risk of some complications, such as cirrhosis or cancer (Gish 2012...
A liver biopsy (in which a needle is inserted into the liver to remove a small piece of tissue for testing) is not routinely needed to diagnose hepatitis B virus infection. A liver biopsy is used to monitor liver damage in people with chronic hepatitis, help decide if treatment is needed,...
(20mM), phosphate (40mM) and histidine (40mM) at pH5.2. “F/T” represents samples that undergone freeze-thaw treatment prior to storage. The data are represented as the geometric mean titer with standard deviation in Balb/C mice (*p<0.001, compared to the original formulation stored at 4...