Interestingly, these two cases had the reduction of the titer of anti-HBs during the treatment, followed by HBV reactivation. These clinical data suggest that the HBV-DNA monitoring is necessary for not only HBsAg-positive but also HBsAg-negative myeloma patients with anti-HBc-positive and/or ...
All the mothers of neonates who had an HBV vertical infection were hepatitis B e antigen (HBeAg)-positive. Among the HBsAg-positive neonates, three were HBeAg-positive and had an HBV DNA titer of 1.0 × 10(8) copies/mL.The HBV prevalence of mothers was 3.32% (308/9,281), and their ...
In HBeAg negative chronic hepatitis B, an HBsAg level < 1,000 IU/mL and an HBV DNA titer < 2,000 IU/mL allow the accurate identification of inactive carriers. On pegylated-interferon (PEG-IFN) treatment, HBsAg quantification allows identifying, as early as week 12 PEG-IFN therapy, ...
Serum hepatitis B virus (HBV) RNA is a surrogate biomarker for intrahepatic covalently closed circular DNA (cccDNA) transcriptional activity and persistence. In this retrospective study, we investigated its presence, levels and composition in ab initio Hepatitis B e antigen (HBeAg) negative chronically...
148-1).30 The complete (negative) strand contains a protein covalently linked to its 5′ terminus.31 The incomplete (plus) strand displays variable length and bears a 5′ capped oligoribonucleotide at its 5′ end (see Fig. 148-2).32 The asymmetry of the DNA strands reflects the ...
Or inoculation of hepatitis B vaccine may also lead to this phenomenon, indicating resistance already. The hepatitis B surface antibody is weak positive, generally is not contagious, but the hepatitis B antibody titer will gradually decline along with the time, so generally strengthens injection once...
Hepatitis A virus antibodies appeared reliably after inoculation with inactivated vaccine, persisting for at least 3 years. Although seroconversion rate was not age- or sex-dependent, the acquired titer was higher in children and females than in elderly males. 展开 关键词:...
Ninety-two healthy individuals who were negative for antibodies to hepatitis B antigen (anti-HBs) were vaccinated against hepatitis B according to a standardized schedule. At selected times, antibody titers and lymphoproliferative capacity to hepatitis B surface antigen (HBsAg) were determined. DNA ...
molecule or virus particle is maintained in a vaccine. Since short synthetic peptides lack any tertiary or quaternary conformation, most antibodies raised against these molecules are incapable of binding to whole virions. When neutralizing antibody is present after injection of a peptide, the titer ...
[49], Tab. 15, S. 747) genannten Personen ist eine Überprüfung des Anti-HBs-Titers empfohlen, wobei oft ein unzureichender Titer unter 100 IU/L festgestellt werden wird. Für bestimmte Patientengruppen, z. B. Dialysepatienten, wird eine höhere HBsAg-Dosis empfohlen. Bei ...