A substantial proportion of patients with chronic hepatitis B (CHB) do not fall into any of the defined phases and are considered to be in the "gray zone" or "indeterminate phase." Most of the current clinical practice guidelines have no recommendations for antiviral treatment for them. ...
Liu, YC., Jeng, WJ. Should Indications for Antiviral Therapy for Hepatitis B Be Broadened to Include Immune-Tolerant Patients, Inactive Carriers, or Patients in the “Gray Zone”?.Curr Hepatology Rep Download citation
gray zoneindeterminantA substantial proportion of patients with chronic hepatitis B (CHB) who do not fit into any of the usual immune states are considered to be in the "gray zones ". We aimed to investigate the distribution and characteristics of this gray zone in a large cohort of CHB ...
hepatitis Cnew alternative methodsvirusesAims: Hepatitis-C virus antigen (HCV-Ag) detection requires retesting for samples with gray zone results (GzR), adding cost and time and decreasing reliability. Our aim in this study was to evaluate the frequency and significance of GzR during the use ...
A few cases of hepatitis B virus (HBV) reactivation during anti-viral therapy against hepatitis C (HCV) have been reported. However, the information regarding the real impact of this phenomenon is scarce. To evaluate the risk of HBV reactivation during anti-viral therapy against HCV with an ...