On screening for HBcAg Ig M, 15 (0.1%) were found to be positive and none were HBsAg reactive. There was no significance of difference in the mean age between reactive and non-reactive donors. Conclusion:Evaluating the usefulness of anti-HBc screening is critical. Anti HBcAg IgM screening ...
Non–exposed Negative Negative c Empty Cell Low–reactived Negative Past infection: Resolved-HCV infection Positive Negative Chronic HCV infection Positive Positive Anti-HBc, antibodies to hepatitis B core antigen; anti-HBs, antibodies to HBsAg; anti-HCV, antibodies to HCV; HBsAg, hepatitis B...
[94,95], exploring novel antigens such assynthetic peptidesandlipopeptideparticles, mutants of HBsAg protein, a DNA sequence that contains part of HBV and the hepatitis Bcore proteinHBcAg[79]as well as exploring alternate routes of delivery (mucosal) and novel dosage forms such as freeze dried...
Table 1 shows a comparison of the occurrence of HEV in samples from swine and humans obtained between 2002 and 2005. The patient serum samples were reactive for anti-HEV IgM but not for anti–hepatitis A or anti–hepatitis B core antigen IgM. Samples from healthy subjects and blood donors w...
The positivity was defined as the absorbance of the negative control mean plus the factor of 0.05 according to the manufacturer's instruction manual. N = Non-reactive and R = Positive reactivity. B. Detection of anti-HBc antibodies Study week 1-18 19 20 21 22 23 24 25 26 27-30 34 37...
hepatitis B core antigen; qRT-PCR, quantitative reverse transcription PCR; FRAP, fluorescence recovery after photobleaching; FLIP, fluorescence loss in photobleaching; Nqo1, NAD(P)H quinone oxidoreductase 1; Gstm1, glutathione S-transferase M1; Cyp2a5, cytochrome P450 2A5; PB1, Phox and Bem1p;...
Hepatitis B virus (HBV) infection still remains a major public health issue in the Asia–Pacific region. Most of the burden of HBV-related disease res
Chronic hepatitis B CVD: Cardiovascular disease CAP: Controlled attenuated parameter CRP: C-reactive protein DNA: Deoxyribonucleic acid DXA: Dual-energy X-ray absorption EASL: European Study of the Liver FGF-21: Fibroblast growth factor 21
Key Words: Alcoholic liver disease; Alcoholic steatosis; Alcoholic hepatitis; Gut microbiota; Lipopolysaccharide; Steroid non-response Core tip: With better treatment options available for other liver diseases like viral hepatitis the proportion of alcoholic liver disease is on the rise. Alcoholic hepati...
For the next 16 years, patients with non-A non-B hepatitis became increasingly recognized as having a form of chronic liver disease. In 1989 Choo et al.117 published the first account of HCV, which was further described as a single-stranded, enveloped, positive-sense RNA virus. It is ...