Fig. 1. Hepatitis B virus. (A) Overview of the structure of the HBV genome, (B) the structure of HBsAg and (C) characteristics of antibodies against HBV’s viral antigens (C). ds, double stranded; HBcAb, antibodies against HBcAg; HBeAg, antibodies against HBeAg; HBsAb, antibodies against...
hepatitis B virus (HBV) DNA value associated with spontaneous or antiviral therapy–related hepatitis B e antigen (HBeAg) clearance, and to determine whether there is an HBV DNA value that can be used to differentiate inactive carriers from patients with HBeAg-negative chronic hepatitis B infection...
This was clearly true of the early research into sequencing, cloning and expressing the hepatitis B surface antigen, which represented a substantial scientific achievement in its own right, resulting in four publications in Nature in the course of 1979 alone. But achieving expression of the surface...
Nevertheless, the POC assay offers advantages for testing in both developed and resource-limited countries due to its low cost (0.50$) and immediately available results. 展开 关键词: diagnosis Hepatitis B S antigen point-of-care variant DOI: 10.1111/jvh.12257 被引量: 18 年份: 2014 ...
Data showed that the prevalence rate of hepatitis B surface antigen has fallen continuously in the country particularly among children under 5 years old, where it has been controlled below 1 percent. Hepatitis B is one of the most burdensome infectious diseases globally and ...
In addition to HBsAg, HBeAg, and anti-HBs, there have been growing interest in the use of other biomarkers for HBV detection, including HBV viral load, alanine aminotransferase (ALT), and hepatitis B core-related antigen (HBcrAg). Given that ALT and HBcrAg are both protein biomarkers, they ...
A diverse B-cell repertoire is essential for recognition and response to infectious and vaccine antigens. High-throughput sequencing of B-cell receptor (BCR) genes can now be used to study the B-cell repertoire at great depth and may shed more light on B
HLA antigensT-lymphocytes,cytotoxicObjective To investigate the expression feature of hepatitis B virus(HBV)-specific cytotoxic T lymphocytes(CTL),and analyze the role of CTL in immune response.Methods Peripheral venous blood was collected from 40 acute hepatitis B(AHB) patients hospitalized from Oct...
Plasma was obtained by centrifugation at 3000 rpm for five minutes and aliquoted into vials for the different analyses, mainly retinol, tocopherol, HIV viral load, HBV surface antigen, and AF-ALB. The vials containing plasma for retinol and tocopherol analysis were wrapped ...
et al. Posttransfusion hepatitis after exclusion of commercial and hepatitis-B antigen-positive donors. Ann. Intern. Med. 77, 691–699 (1972). Article CAS PubMed Google Scholar Prince, A. M. et al. Long-incubation post-transfusion hepatitis without serological evidence of exposure to ...