Australia antigen and the quest for a hepatitis virus. Am J Dig Dis. 1969 Mar; 14 (3):189–194.Sutnick, A. I. , W. T. London and B. S. Blumberg 1969 Australia antigen and the quest for a hepatitis virus . Amer. J. Digestive Diseases , 14 : 189 ....
Data showed that the prevalence rate of hepatitis B surface antigen has fallen continuously in the country particularly among children under 5 years old, where it has been controlled below 1 percent. Hepatitis B is one of the most burdensome infectious diseases globally and c...
Meanwhile, the 2.1 kb RNA synthesizes the other two surface antigens, HBV middle (M-HBs, which includes preS2 region) and small surface antigen (S-HBs). The 0.7 kb RNA is responsible for the synthesis of the HBV X protein (HBx). After the viral polymerase binds to pgRNA, the complex...
To determine a patient’s HBV status, HBsAg is always tested alongside anti-HBc and anti-HBs (Fig.1). A positive HBsAg antigen indicates ongoing infection and infectivity. Initially, the majority of infections are hepatitis B e antigen (HBeAg)-positive. During the course of a chronic infection...
Insights into the immunopathogenesis of chronic HBV infections are fundamental in the quest for novel treatment approaches aimed at a functional cure. While much is known about the ineffective HBV-specific T-cell responses that characterise persistent HBV replication, B cells have been left largely und...
HLA antigensT-lymphocytes,cytotoxicObjective To investigate the expression feature of hepatitis B virus(HBV)-specific cytotoxic T lymphocytes(CTL),and analyze the role of CTL in immune response.Methods Peripheral venous blood was collected from 40 acute hepatitis B(AHB) patients hospitalized from Oct...
et al. Posttransfusion hepatitis after exclusion of commercial and hepatitis-B antigen-positive donors. Ann. Intern. Med. 77, 691–699 (1972). Article CAS PubMed Google Scholar Prince, A. M. et al. Long-incubation post-transfusion hepatitis without serological evidence of exposure to ...
Possibly, B cells cross-reacting with HCV and self-antigens discharged from hepat- ocyte preferentially proliferate in the liver microenvironment to serve as a protective immunity against both chronic hepatitis C (CHC) and ongoing oncogenic processes, given the observation that HCV-CG patients show ...
Induction of tolerance towards antigens that drive susceptibility or pathology may be considered a new mode of treatment for several infections. Hepatitis B virus is a non-cytopathic virus, and oral immune regulation was shown to be effective in modulation of the immune-mediated liver injury. 关键...
Ikeda K, Marusawa H, Osaki Y, et al. Antibody to hepatitis B core antigen and risk for hepatitis C-related hepatocellular carcinoma: a prospective study. Ann Intern Med. 2007;146:649–56. Google Scholar Fattovich G, Pantalena M, Zagni I, et al. Effect of hepatitis B and C virus inf...