The Hepatitis B virus (HBV) nucleocapsid self-assembles into virus-like particles and can be exploited for the presentation of various foreign B- and T-cell epitopes for HBV and non-HBV vaccine design. A construct containing a codon-optimized truncated HBV nucleocapsid gene (HBc153) was ...
The risk of developing a chronic infection is highest for infants infected at birth or prior to six months of age. HB vaccine is, therefore, given at birth and is followed by two or three doses in order to prevent perinatally- acquired chronic infection and early childhood HB virus ...
For a long period, only canineAdVshad been known to infect carnivores. CAdV-1 is the causative agent ofinfectious canine hepatitis(the so-called Rubarth's disease), a life-threatening disease ofpuppies. Regularvaccinationworldwide has decreased the number of clinical cases. Viruses, serolog...
WHO recommends that all infants should receive their first dose of vaccine as soon as possible after birth, preferably within 24 hours. Yet Canada's hepatitis B vaccination policy varies widely between provinces and territories. Most of the provinces with large populations vaccinate children when they...
A pilot study of the CY-1899 T-cell vaccine in subjects chronically infected with hepatitis B virus. Heathcote J,Mchutchison J,Lee S,et al. Hepatology . 1999Heathcote J, McHutchison J, Lee S, Tong M, Benner K, Minuk G, et al. A pilot study of the CY-1899 T-cell vaccine in ...