Then, the recombinant DNA technology enabled the development of recombinant hepatitis B vaccine. A series of three doses vaccine can elicit long-term protection more than 30 y. Concurrent use of hepatitis B immunoglobulin and hepatitis B vaccine has substantially reduced the mother-to-child ...
Hepatitis B is a significant public health concern and a leading cause of liver cancer across the world. In Australia, hepatitis B is largely endemic in migrant communities, particularly amongst the Chinese and Vietnamese communities. Negative attitudes towards hepatitis B can be a major barrier to...
Keywords: Hepatitis B vaccine, Hepatitis B elimination, Birth dose, Region of the Americas, Mother-to-child-transmission Background Hepatitis B (HB) is a liver infection caused by the Hepatitis B virus (HBV), transmitted by percutaneous or mucosal exposure to blood or body fluids of an in- ...
As the infection invades the liver, the HBV cells multiply causing inflammation and further symptoms. Most individuals avoid contracting hepatitis B by getting the hepatitis B vaccine; however, some instances still occur. Behaviors that heighten the risk of contracting hepatitis B include having ...
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A Hepatitis C Virus (HCV) Vaccine Comprising Envelope Glycoproteins gpE1/gpE2 Derived from a Single Isolate Elicits Broad Cross-Genotype Neutralizing Antib... Although a cure for HCV is on the near horizon, emerging drug cocktails will be expensive, associated with side-effects and resistance mak...
A vaccine has been developed in last decade of twentieth century for hepatitis A virus, which is administered mostly in the developed world i.e. U.S and Japan. Treatment for these infections is mostly supportive; however, in the case of fulminant hepatitis the liver transplantation might be ...
Current preventive strategies in resource-limited settings fail mainly due to prohibitive costs of hepatitis B immunoglobulin (HBIG) and a high proportion of homebirths, meaning both HBIG and hepatitis B birth dose vaccine are not given. A new strategy for PMTCT without the necessity of HBIG, ...
Herremans M, Bakker J, Duizer E et al (2007) Use of serological assays for diagnosis of hepatitis E virus genotype 1 and 3 infections in a setting of low endemicity. Clin Vaccine Immunol 14:562–568 Article CAS PubMed PubMed Central Google Scholar Hesamizadeh K, Sharafi H, Keyvani ...
function of its gene product, a type-III interferon (IFN-λ3), remains to be elucidated. Human BDCA3+DCs have also been shown to be a potent producer of IFN-λ3 in HCV infection, suggesting the possibility that BDCA3+DCs could play a key role in developing therapeutic HCV vaccine. ...