Our analysis supports the CDC recommendation to test all HCV IgG-reactive sera for HCV RNA.doi:10.1016/j.diagmicrobio.2021.115311Harry E. PrinceElizabeth M. MarloweDale S. SchwabDiagnostic Microbiology and Infectious Disease
An effective HIV-1 vaccine remains a critical unmet need for ending the AIDS epidemic. Vaccine trials conducted to date have suggested the need to increase the durability and functionality of vaccine-elicited antibodies to improve efficacy. We hypothesiz
Because gp120-specific IgG accounted for a very low frequency of serum total IgG, as described in some studies (Foudaet al.2011; Yuet al.2016), we defined the total IgG as the amount of nonspecific antibodies. In our previous study, we found that HIV-1 gp120 induced higher levels of n...
Both β-sitosterol and stigmasterol can induce the apoptosis of human hepatocarcinoma cells and significantly increase cellular reactive oxygen species and Ca2+ levels [43]. KEGG and GO analysis were performed to explore the roles of the predicted YGJ targets. GO analysis indicated that the potential...
Hepatitis C virus (HCV) poses a growing threat to global health as it often leads to serious liver diseases and is one of the primary causes for liver transplantation. Currently, no vaccines are available to prevent HCV infection and clinical treatments
17. The polynucleotide of claim 16, encoding an antibody or antigen-binding fragment comprising a mouse, rabbit, goat, rat, or human IgG heavy chain constant region. 18. The polynucleotide of claim 1, encoding an antibody or antigen-binding fragment 7, comprising a kappa light chain or a la...
Alternatively, an active fragment of the neutralizing anti-HCV antibodies of the invention can be obtained or produced by a method comprising the steps of: (i) obtaining a crude preparation of an antibody comprising said fragment by means of recombinant expression of the antibody or by means of...
A p-value of <0.05 for a two-tailed test was used as the criterion of significance for all statistical tests. Results The overall prevalence of anti-HEV IgG in HIV-infected patients was 6.7% (24/360) and in blood donors was 7.1% (20/281); the difference between these two groups was...
CodeGenotypeStrainOriginSample TypeAnti-HEV - IgM/IgGAccession number 8567/13 1a India Plasma n.d. n.a.# 8568/13 s 1a Kol-15 India Stool n.a. n.a.# 8569/13 1e Sudan Plasma +/- n.a.# 8570/13 3b JRC-HE3 Japan Plasma +/- AB630971 8571/13 3c Oct 8 Sweden Plasma -/- ...
(r= 0.367,p= 0.001) and insulin resistance and inflammation prognostic ratios/indices. A receiver operating characteristic (ROC) curve revealed that adding LAIR-1+Tc% to AFP can distinguish HCC transformation in the Egyptian patients’ cohort. Upregulated LAIR-1 expression on Tc could be a ...