The most common side effects are hemorrhage (bleeding), thrombocytopenia (decreaseplatelet count), heparin induced thrombocytopenia (HIT), heparin induced thrombocytopenia and thrombosis (HITT), injection site discomfort/irritation, allergyor hypersensitivity type reactions, and increase inliverenzymes. Hepari...
An audit of the Utrecht Patient Oriented Database of patients treated with low-molecular-weight heparin (LMWH) at the University Medical Center Utrecht revealed low compliance with platelet count monitoring as well as initial management of suspected heparin-induced thrombocytopenia (HIT). Limitations to...
Paradoxically, despite a very low platelet count, patients who suffer from heparin-induced thrombocytopenia are at risk for arterial or venous thrombosis. In this review article, there are discussed about pathogenesis of heparin-induced thrombocytopenia, other causes of thrombocytopenia, clinical features,...
Thrombocytopenia: Monitor platelet count during therapy; discontinue heparin in HIT or HITT is suspected. (5.4) Hypersensitivity Reactions: Use in patients with prior reactions only in life-threatening situations. (5.5) Heparin Resistance: Increased resistance to heparin is frequently encountered in fever...
Thrombocytopenia Thrombocytopenia has been reported to occur in patients receiving heparin with a reported incidence of 0 to 30% up to 30%. Platelet counts should be obtained at baseline and periodically during heparin administration. Mild thrombocytopenia (count greater than 100,000/mm3) may remain ...
In the child with cyanotic congenital heart disease, hemostasis is further impaired due to polycythemia, low platelet count and altered function,16 reduced factors V, VII, and VIII, and increased fibrinolysis. The degree of derangement is related to the degree of cyanosis.37,38 Despite improvements...
Pregnancy complicated by preeclampsia–eclampsia with the syndrome of hemolysis, elevated liver enzymes, and low platelet count: how rapid is postpartum recovery? Obstet Gynecol 1990;76:737–741. Article Google Scholar Magann EF, Perry KJ, Meydrech EF, Harris RL, Chauhan SP, Martin Jr JN ....
It is a nonimmune disorder that results from the direct effect of heparin on platelet activation. It does not require any specific management; patients can be maintained on heparin products, as the platelet count typically normalizes with continued heparin therapy. [1] Type 2 HIT is an ...
BACKGROUND: Summaries of product characteristics (SPCs) and clinical guideline recommendations are available for monitoring the platelet count for heparin-induced thrombocytopenia (HIT) in patients receiving low-molecular-weight heparin (LMWH). Testing for the presence of heparin-platelet factor 4 antibodi...
BackgroundPulmonary embolism (PE) occurs in 50% or more of patients with proximal deep-vein thrombosis. Low-molecular-weight heparin treatment is