While these are both heparins, they have slightly different mechanisms of action and are administered differently to the body, hence having different monitoring parameters. In the health care setting, UFH is called "heparin," while LMWH is called "enoxaparin" or "Lovenox" (brand-name). Lovenox...
We appreciate the comments of Drs Hughes and Gonzalez. However, it seems that they have misunderstood the mechanism of action of LMWH and made an incorrect conclusion in their letter. Increasing the dose of heparin compensates for the re... JT Owings - 《Archives of Surgery》 被引量: 0发表...
Heparin and oral anticoagulants in the treatment of brain ischemia The use of heparin, heparin analogues, and oral anticoagulation in the treatment of brain ischemia remains controversial. We review the mechanism of action... CLR Caplan - 《Journal of the Neurological Sciences》 被引量: 23发表: ...
byuseofasensitivewashedplateletactivationassay •Morespecificthanapositiveantigenassay WarkentinTE,GreinacherA.Chest.2004;126:311S-337S.FrequencyofHIT •RiskofHITwithrespecttotypeofheparin •Bovinelungunfractionatedheparin(UFH)•PorcinemucosalUFH•Low–molecularweightheparin(LMWH)•RiskofHITincreaseseach...
7 Compared with unfractionated heparin, its recent derivates, low-molecular-weight heparins (LMWH) mainly inhibit factor Xa, have a longer plasmatic half-life, require limited surveillance, and are, therefore, highly suitable for treating lower-risk conditions and outpatients.7 Warfarin is the ...
Objective Evaluation of the effectiveness and safety of long-term low molecular weight heparin (LMWH) in patients with antiphospholipid syndrome (APS) that... G M.,Genievskaya,and,... - 《International Journal of Gynecology & Obstetrics》 被引量: 6发表: 2000年 Mechanism of action of minoxidil...
Buyue Y, Misenheimer TM, Sheehan JP (2012) Low molecular weight heparin inhibits plasma thrombin generation via direct targeting of factor IXa: contribution of the serpin-independent mechanism. J Thromb Haemost 10: 2086-2098. doi: 10.1111/j.1538-7836.2012.04892.x PMID: 22905983...
Reduction of the whole-cell number does not directly explain the mechanism of action or distinguish between general toxicity and controlled alterations to cell processes. We therefore sought to probe how internalized heparin induced cellular effects. We hypothesized that internalized heparin induces cell-...
While the mechanism underlying HSPG-mediated internalization and the antiviral activity of heparin are well understood for many HSPG-dependent viruses (18), it has only recently begun to be investigated for SARS-CoV-2. Indeed, among the various coronaviruses, the SARS-CoV-2 spike is unique in ...
Medical Analysis, Peking University, Beijing 100191, China Aim: To investigate the inhibitory effects of heparin on PC-3M cells proliferation in vitro and B16-F10-luc-G5 cells metastasis in Balb/c nude mice and identify the protein expression patterns to elucidate the action mechanism of heparin...