There are no available data on heparin sodium use in pregnant women to inform a drug-associated risk of major birth defects and miscarriage. In published reports, heparin exposure during pregnancy did not show evidence of an increased risk of adverse maternal or fetal outcomes in humans. No tera...
Avoid using heparin in the presence of major bleeding, except when the benefits of heparin therapy outweigh the potential risks. Hemorrhage can occur at virtually any site in patients receiving heparin. Fatal hemorrhages have occurred. Adrenal hemorrhage (with resultant acute adrenal insufficiency), ova...
cardiac tamponadehyperkalemiaHeparin, a commonly used anticoagulant agent, is frequently used in patients undergoing hemodialysis. As with most medications, heparin has a significant side effect profile. Two of its most important side effects, major bleeding and hyperkalemia, may be devastating without ...
Side effectsThe major adverse reaction resulting from heparin therapy is hemorrhage. Bleeding can occur in the urinary or gastrointestinal tract and in the adrenal gland. Subdural hematoma, acute hemorrhagic pancreatitis, hemarthrosis, and wound ecchymosis also occur. The incidence of life-threatening he...
The third and major group of side-reactions is related to inappropriate manifestations of heparin's therapeutic properties. Most of these are avoidable by careful technic of administration (being local ecchymoses of minor or major proportions). Some are due to inappropriate dosages in susceptible ...
The clinical effects of heparin are meritorious, but side effects do exist. Bleeding is the primary untoward effect of heparin. Major bleeding occurs in 1% to 33% of patients who receive heparin therapy.45 Additional important untoward effects of heparin therapy that are discussed in this article...
Avoid using heparin in the presence of major bleeding, except when the benefits of heparin therapy outweigh the potential risks. Hemorrhage can occur at virtually any site in patients receiving heparin. Adrenal hemorrhage (with resultant acute adrenal insufficiency), ovarian hemorrhage, and ...
BACKGROUND: Patients who have had major trauma are at very high risk for venous thromboembolism if they do not receive thromboprophylaxis. We compared low-... WH Geerts,RM Jay,KI Code,... - 《N Engl J Med》 被引量: 1452发表: 1996年 Comparison of unfractionated heparin, low-molecular-wei...
Heparin is a polysaccharide having a mixture of linear anionic units of 2-O-sulfo-α-iduonic acid and 2-deoxy-2-sulfamino-6-O-sulfo-α-d-glucose as its major repeating disaccharide and minor amounts of β-d-glucuronic acid and 2-acetamido-2-deoxy-α-d-gulucose. Heparin is widely used...
Avoid using heparin in the presence of major bleeding, except when the benefits of heparin therapy outweigh the potential risks. Hemorrhage can occur at virtually any site in patients receiving heparin. Adrenal hemorrhage (with resultant acute adrenal insufficiency), ovarian hemorrhage, and ...