Growth factor- and heparin-dependent regulation of constitutive and agonist-mediated human endothelial barrier function. Am J Physiol Heart Circ Physiol 291: H2126-H2135.Moy AB, Blackwell K, Wu MH and Granger HJ (2006) Growth factor- and heparin-...
Helicobacter pylori interacts with heparin and heparin-dependent growth factors. FEMS Immunol Med Microbiol 1995; 12: 265±272. F Ascencio,H Hansson,O Larm,... - 《Fems Immunology & Medical Microbiology》 被引量: 0发表: 1995年 Gastrin induces heparin-binding epidermal growth factor-like growth...
Interaction of androgen-induced autocrine heparin-binding growth factor with fibroblast growth factor receptor on androgen-dependent Shionogi carcinoma 115... Stimulation of a Shionogi carcinoma 115-derived cultured cell line (SC-3) with androgen resulted in secretion of heparin-binding growth factor. In...
Many factors are intimately involved in the process of wound healing by regulating HB-EGF shedding and signaling. Injury leads to ATP release, which then activates its purinergic receptors and induces MMP-dependent ectodomain shedding of HB-EGF in CECs.41 The nonreceptor tyrosine kinase Src is imp...
BACKGROUND: Heparin-induced thrombocytopenia, defined by the presence of heparin-dependent IgG antibodies, typically occurs five or more days after the sta... TE Warkentin,MN Levine,J Hirsh,... - 《N Engl J Med》 被引量: 5394发表: 1995年 Bivalirudin and provisional glycoprotein IIb/IIIa bloc...
To further investigate whether inhibition of Alp expression by HB-EGF is mediated through the MAPK- or PI3K/Akt-dependent pathway, we treated C2C12/ Runx2Dox cells with an inhibitor of any of the aforementioned pathways, and found that Alp expression was also upregulated after treatment (Figure...
while the delayed reaction involves the production of heparin-dependent antiplatelet antibodies and the clearance of platelets from the blood. Heparin-associated thrombocytopenia may be associated with irreversible aggregation of platelets (white clot syndrome). Additional untoward effects of heparin treatment...
In vitro studies showed sustained release of all the growth factors for almost 60 days and the rate of release was directly dependent on the amount of heparin in Hep-NS. The released growth factors retained their bioactivity as assessed by a cell proliferation assay. This heparin nanosponge is ...
(Figure 11.4). Heparin is a strong anticoagulant molecule and is used in anticoagulation therapy during hemodialysis and extracorporeal blood circulation. The antithrombogenic activity ofimmobilized heparinis dependent on its density and mobility. Also, maintaining the biological activity of heparin is ...
Hsulf-1 expression reduced both anchorage-dependent and -independent cell growth and decreased FGF-2 mediated cell growth and invasion in this cell line. Conclusion High expression of Hsulf-1 occurs in the stromal elements as well as in the tumor cells in pancreatic cancer and interferes with ...