Heparin as a natural anticoagulant has frequently been suggested for use in blood transfusions, but the difficulty in obtaining a pure and potent product free from toxic effects, as well as the high cost of production, has been a hindrance to its trial and use. Mason1 in 1924 reported some...
Treatment of acute and chronic consumptive coagulopathies (disseminated intravascular coagulation); • Prevention of clotting in arterial and cardiac surgery; • Prophylaxis and treatment of peripheral arterial embolism; • Anticoagulant use in blood transfusions, extracorporeal circulation, and dialysis...
dextran, phenylbutazone, thienopyridines, dipyridamole, hydroxychloroquine, glycoprotein IIb/IIIa antagonists (including abciximab, eptifibatide, and tirofiban), and others that interfere with platelet-aggregation reactions (the main hemostatic defense of heparinized patients) may induce bleeding and should ...
nouna polysaccharide produced in basophils (especially in the lung and liver) and that inhibits the activity of thrombin in coagulation of the blood Synonyms Lipo-Hepin Liquaemin Related Words anticoagulant medication decoagulant polyose polysaccharide ...
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Heparin may also be employed as an anticoagulant in blood transfusions, extracorporeal circulation, and dialysis procedures and in blood samples for laboratory purposes. CONTRAINDICATIONS Heparin sodium should NOT be used in patients with the following conditions: Severe thrombocytopenia; When suitable ...
We found that SYTOX-positive polymers appear in heparinised blood under flow. These polymers typically associate with platelet aggregates and their length (reversibly) increases with shear rate. Immunostaining revealed that of the heparin-binding proteins assessed, they only contain histones. In ...
CONCLUSIONS: Heparin does not increase blood loss or the need for blood transfusion during surgery. Heparin is not necessary to prevent distal thrombosis when the aorta is cross clamped. The results of the study are consistent with the known mechanisms leading to intraoperative MI and strategies ...
HEPARIN-INDUCED THROMBOCYTOPENIA, PARADOXICAL THROMBOEMBOLISM, AND OTHER SIDE EFFECTS OF HEPARIN THERAPY Heparin, first used to prevent the clotting of blood in vitro, has been clinically used to treat venous thrombosis for more than 50 years. Although several... Jeanine,M.,Walenga,... - 《Medica...
Anticoagulant use in blood transfusions, extracorporeal circulation and dialysis procedures. Heparin and Dextrose Dosage and Administration Recommended Adult Dosages: • Therapeutic Anticoagulant Effect with Full-Dose Heparin* (2.3) Intermittent Intravenous Injection Initial Dose 10,000 Units, either ...