The Hep B vaccine, the first of many such vaccines that are routinely administered to US children, is injected into the newborn shortly after birth. It is given over three doses: the minimum recommended dosing intervals are 4 weeks between the 1st and 2nd and 8 weeks between the 2nd and...
Gentile A, Umido V, Czerniuk P, Nacul J, Seigelchifer M, Hilbert AK, et al. Immunogenicity and reactogenicity of a combined fully liquid DTPw-HepB- Hib pentavalent vaccine in healthy infants: no clinically relevant impact of a birth dose of hepatitis B vaccine. Int J Infect Dis 2011;...
The birth dose of HepB vaccine did not seem to influence the safety pattern of the DTPw–HepB–Hib combination vaccine. Conclusions The present study demonstrated that the fully liquid DTPw–HepB–Hib vaccine was safe and immunogenic when administered using a 2–4–6 months immunization schedule...