At the time, the vaccine contained aluminum and mercury, both known neurotoxins that can cross the blood-brain barrier and accumulate in the brain. While the mercury was phased out starting in 1999, it still contains aluminum as an “adjuvant”, the purpose of which is to provoke a stronger...
which could grow steadily in the GHK-21 cells with a viral titer of 1010 FFU/mL was successively obtained.This recombinant virus providing strong immunogenicity coupled with loss of pathogenicity should be considered as the...
A multi-centre, double-blind, parallel-group comparative study to assess the efficacy and safety of a single dose of either Hepagene™ or Engerix®B in subjects with an inadequate response to previous vaccination with an S-containing hepatitis B vaccine...
Oral vaccine deliveryImmunological adjuvantCarbon nanoparticlesThe purpose of this study is to develop a novel kind of adjuvant for oral vaccine delivery. In order to effectively prevent the degradation of antigens in the gastrointestinal tract and optimize the uptake for M cells, a novel kind of ...