We have previously observed the downregulation of TMEM2 in the liver tissue of patients with chronic hepatitis B virus (HBV) infection and in HepG2.2.15 cells with HBV genomic DNA. In the present study, we investigated the role and mechanism of TMEM2 in HepG2 and HepG2.2.15 during HBV ...
The graph shows the statistical analysis results (n = 3, mean ± SD). **P < 0.01 in comparison with untreated cells, *P < 0.05 in comparison to cells treated with As2O3 or DNCB for 24 h. (C) HepG2 cells were treated as indicated in B, and subjected to subcellular fractionation. ...
of LDLR. Approximately, > 95% transduction efficiency and minimal cell death were obtained with a seeding density of 3 × 104cells infected with viral particles at a multiplicity of Infection (MOI) of 3. The transduced stable cells were maintained media at a final concentration of 10 ...
ingonthetertileofriskscoresandstatusofhepatitisB/Cvirusinfection.Combining risk-scoretertilelevelsandhepatitisvirusstatustostratifyparticipantswasmoresensitive thancurrentguidelinesforHCCdetectionwithin10years(89.4%vs.76.8%),especially foryoung-onsetHCCs50years(79.4%vs.40.6%),underslightlylowerspecificity (67.8...
Among several etiologic factors, including infection from hepatitis B and C viruses, alcohol, and aflatoxin, HBV infection is predominant in HCC pathogenesis in India [4]. Sorafenib is an FDA-approved first-line systemic therapy for advanced HCC. Sorafenib, a multikinase inhibitor for inhibiting ...
BDE-99 enriched only four pathways, with Salmonella infection being the top significant, plus the bacterial invasion of epithelial cells, the gap junction, and the spliceosome pathways, mostly featuring induced DEPs and with no notably relevant hubs (Figure S1b). The most significant pathway affecte...
B.music helps him to see the world virtuallyC.he motivates the kids to realize their dreamD.he desires to challenge something impossible 答案(1)C.细节理解题。根据第一段"We didn't have health insurance at the time,and when I got a third infec...
M. et al. Reduced Expression of DNA Damage Repair Genes High Mobility Group Box1 and Poly(ADP-ribose) Polymerase1 in Inactive Carriers of Hepatitis B Virus Infection-A Possible Stage of Viral Integration. J Clin Exp Hepatol. 3, 89–95 (2013). Article PubMed PubMed Central Google Scholar ...
Graph that resulted from the joint pathway enrichment analysis using MetaboAnalyst of the proteins and metabolites that altered significantly (p value < 0.05) in resistant Hep3B cells vs. parental Hep3Bcells. Nodes are colored according to p value. Significant pathways are colored red, while non-...
The development of cancer cells is multifactorial and occurs due to the causative agents released during stress, exposure to radiation or infection. This study hypothesizes that W. somnifera can be expressed as a potential agent for the elimination of the excess oxidative species and toxins ...