Hepatocellular carcinoma (HCC) is a leading cause of cancer-related death worldwide. Despite systemic and molecularly targeted therapies commonly used in H
Interestingly, 0.5 μM 1–3 significantly caused HepG2 arrest at S-phase, which was associated with the up-regulation of p53, p21, p27, Chk1 and Chk2 proteins, and decrease in cyclin A, CDK2, Cdc25A, PCNA proteins. In addition, 1–3 induced HepG2 apoptosis via a caspase-...
The absorption was determined at a wavelength of 517 nm by an ultra-violet−visible (UV−Vis) spectrophotometer. The blank group was 50% ethanol solution, and the control group was 3 mL of 50% ethanol with 1 mL of DPPH solution. An assay kit was used to determine to the scavenging ...
How Common Is Hepatitis A? The most common hepatitis viruses in the U.S. are hepatitis A, B, and C. According to the Centers for Disease Control and Prevention (CDC), since 1995, rates have declined by more than 95% thanks to the vaccine becoming available.1In 2016, there were only ...
Strains were characterized for the presence of A, B and CDT toxin genes by multiplex PCR, as previously described [31]. These PCR ribotypes were subsequently analyzed using the WEBRIBO web database [32]. Strains were preserved frozen (−80 ◦C) in a 20% glycerol 80% Brain Heart In...
(WHITE), cytochrome b-561 family protein, CDC-like kinase 1 (CLK1 HGNC) (protein tyrosine kinase STY), Na+/H+ exchanger regulatory factor (NHERF HGNC), potassium voltage-gated channel subfamily H member 2 (KCNH2), putative MAPK activating protein (PM20, PM21), ras homolog gene family,...