This response, coupled with a "lack of desire," seems to be more prevalent and impactful in US respondents and even more prevalent in the mild to moderate hemophilia US population represented in B-HERO-S. The prevalence of these responses could be due to target joints, a lack of adherence...
Hemophilia is equally distributed among all ethnic groups worldwide. The estimated frequency of hemophilia is around 1 in 10000 live births, and the number of people worldwide living with hemophilia is about 400000.[1][8][9]Hemophilia A is more prevalent (80% to 85% of the total hemophilia...
Inhibitors occurred with a similar prevalence across all eras and were consistently more prevalent in men with severe hemophilia (11.5-17.0%) compared with men with mild hemophilia (2.8-3.6%) (Table 4). Mortality During the study period, a total of 551 deaths were reported. The era A and ...
usually manifested in males and transmitted by females who carry the causative mutation on the X chromosome. Hemophilia B results from a variety of defects in the FIX gene. FIX deficiency is 4-6 times less prevalent than factor VIII (FVIII) deficiency (hemophilia A). ...
For the doses of factor IX concentrate, patients receiving prophylaxis received an average of 41.6 (±11.9) IU/Kg/Injection in 2019, 45.7 (±12.9) IU/Kg/Injection in 2020, and 60.1 (±24.0) IU/Kg/Injection in 2021.Clinically, prophylaxis is more prevalent than reported. Based on insights...
In the past three decades, hemophilia has moved from the status of a neglected and often fatal hereditary hemorrhagic disorder to that of a defined group of well-characterized molecular entities. There is little doubt at the moment that, among the most prevalent monogenic disorders (cystic fibrosis...
treatment available to treat this disorder. Among the types of disorders, type A is predicted to be four times more prevalent than type Balso it is the most commonly occurring type. The types of hemophilia are characterized on the basis of the coagulation factor deficiency present in particular...
In a cohort of Canadian patients with mild hemophilia, 29% were hypertensive as compared to 18% of the control subjects [18]. Rosendaal et al. [17] suggested that hypertension is more likely to be detected because of the intensive medical care received by hemophilia patients. This appeared ...
Extra‐appendicular bleeds were less common, with ocular bleeding (10 rats) and urogenital bleeding (eight rats) being most prevalent, and only a few bleeds being seen in other locations (subcutaneous bleeding, wounds and tail bleeds, penile prolapse resulting from blood clots, and oral and ...
Having no chronic pain was most prevalent in the full adherence group (37.7%), compared to moderate (8.3%) or low (13.9%) adherence cohorts. Chronic pain, both low- and high-levels were least prevalent among people with full adherence. Moreover, people with low adherence were ...