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This bleeding can range from mild to severe. In severe cases, people with hemophilia can bleed to death. Because of the way in which hemophilia is inherited, it almost exclusively affects men. Women can get it, but it is very rare. ...
Hemophilia A can be inherited or acquired. Inherited hemophilia A is caused by a mutation to thefactor VIIIgene on the X chromosome, which is commonly passed down from parents to children. However, in about one-third of cases, the cause is a spontaneous mutation in that gene. Acquired ...
Hemophilia A can be inherited or acquired. Inherited hemophilia A is caused by a mutation to the factor VIII gene on the X chromosome, which is commonly passed down from parents to children. However, in about one-third of cases, the cause is a spontaneous mutation in that gene. Acquired ...
In about two-thirds of cases, hemophilia-causing mutations are inherited from a person’s biological parents; in the other third or so of cases, patients are born with hemophilia despite having no family history of the disease. These instances generally are due to spontaneous mutations that ...
Hemophilia is inherited as an X-linked recessive trait in which the mother must pass on a copy of the defective gene to a male child, and more rarely, both parents must pass on copies of the defective gene to a female child. see hemophilia a, hemophilia b compare von willebrand disease ...
Hemophiliarefers to a group of inherited disorders that cause unusual bleeding. The bleeding happens because part of theblood-- the fluid part called plasma -- has too little of aproteinthat helpsblood clot. Symptoms of hemophilia range from more than usual bleeding after trauma, injury, or sur...
Hemophilia is typically inherited, meaning that it’s passed through the parents’ genes or DNA, although approximately one-third of cases are due to spontaneous mutation, or change in a gene. The genes for hemophilia A and B are carried on the X chromosome. Therefore, hemophilia A is called...
Known since the beginning of the first millennium, the hemophilias are among the most frequent inherited disorders of blood coagulation and definitely the most severe. In the 1970s, with the availability of concentrated preparations of t... Mannucci,M P. - 《Hematology》 被引量: 92发表: 2002...