THE EFFECT OF HEMOPHILIA ON HEALTH RELATED QUALITY OF LIFE IN EGYPTIAN CHILDRENElsafy, Osama RushdyMervatMohammed, AtfyAbdelfatah, Nelly RaafatIshtaiwi, Ishtaiwi ElbahlulJournal of Cardiovascular Disease Research (Journal of Cardiovascular Disease Research)...
There are many instances on record of hemophiliac patients who bled to death from a cut finger or lip. The spontaneous loss of a deciduous tooth has caused fatal hemorrhage. Hemorrhages may occur any place in the body: under the skin, into the muscle and in the mouth, stomach or ...
Rarely, hemophilia C (a deficiency of Factor XI) is encountered, but its effect on clotting is far less pronounced than A or B. Hemophilia A and B are inherited in an X-linked recessive genetic pattern and are therefore much more common in males. This pattern of inheritance means that a...
EFFECT OF DANAZOL ON APTT, COAGULANT FACTOR ACTIVITY AND BLEEDING IN HEMOPHILIAPediatric Research publishes original papers, invited reviews, and commentaries on the etiologies of diseases of children and disorders of development, extending from molecular biology to epidemiology. Use of model organisms ...
After adjustment for age at first treatment, we found no protective effect of breastfeeding on inhibitor formation. 展开 关键词: age at first exposure breastfeeding hemophilia inhibitors DOI: 10.1080/08880010500198764 被引量: 21 年份: 2005
Effect of BAX499 apt- amer on tissue factor pathway inhibitor function and thrombin generation in models of hemophilia. Thromb Res 2012; 130: 948- 55.Gissel M, Orfeo T, Foley JH, Butenas S. Effect of BAX499 aptamer on tissue factor pathway inhibitor function and thrombin generation in ...
Your body can also make antibodies called "inhibitors" against ALPROLIX, which may stop ALPROLIX from working properly. These are not all of the possible side effects of ALPROLIX. Talk to your healthcare provider right away about any side effect that bothers you or does not go away, or if ...
In an effort to control for the effects of aging on physical function, we compared outcomes of men with severe hemophilia to those of men with mild hemophilia within each era. When observed in this framework, there may be evidence that the effect of frequent bleeds in the younger eras of ...
This modification, called PEGylation, increases FVIII’s stability, taking longer for the body to break it down, meaning that the therapy works for longer periods of time after being infused into the bloodstream. This allows for less frequent dosing....
Many severe hemophilia A patients, nearly 30%, develop alloantibodies against administered factor VIII. Inhibitor development represents a major complication and challenge in hemophilia treatment because these alloantibodies inactivate the procoagulant effect of infused factor VIII, thereby inhibiting the respo...