Hemolytic anemia is a disorder in which red blood cells are destroyed faster than they can be made. The destruction of red blood cells is called hemolysis.
Lab tests were consistent with severe hemolytic anemia, including hemoglobin of 6 g/dL, indirect hyperbilirubinemia, elevated lactate dehydrogenase, and a low haptoglobin level. Peripheral blood smear showed dysmorphic red blood cells suggestive of mechanical lysis. The patient required multiple transfusion...
Free Essay: Anemia conditions can be mild or severe, and the Social Security Administration looks closely at the severity of medical symptoms that negatively...
Autoimmune Hemolytic Anemia - Learn about the causes, symptoms, diagnosis & treatment from the Merck Manuals - Medical Consumer Version.
All forms of TMA are associated with hemolytic anemia. Elevated circulating arginase has been associated with a range of pathological states, notably cardiovascular, kidney, neurological and hematological diseases [4]. Arginase 1 is released during hemolysis and elevated levels have been described in ...
Dϩ HUS was defined as a prodrome of enteritis or HC with 1) thrombocytopenia (Ͻ150,000 cells/L); 2) microangiopathic hemolytic anemia (Hb below the third percentile for age- and sex-matched controls) with fragmented red cells on blood smear; and 3) acute renal failure (serum ...
Our group has previously demonstrated findings indicating hemolytic anemia in E. coli O157:H7-infected mice that developed kidney injury [25, 36]. Mice inoculated with E. coli O157:H7 develop hemolysis with fragmentation of red blood cells [36] and decreased red blood cell counts as well as ...
It is thus common experience that some cases of pernicious anemia in deep relapse show weakly positive direct Coombs tests. Not even the most efficient of elution technics will, however, produce an eluate active on other cells. In other words, the findings of a positive direct Coombs test ...
Red blood cell (RBC) protein 4.2 deficiency is often associated with a moderate nonimmune hemolytic anemia, splenomegaly, and osmotically fragile RBCs resembling, but not identical to, hereditary spherocytosis (HS). In the Japanese type of protein 4.2 deficiency (protein 4,2Nippon...
Hemolytic anemia from PHZ treatment is believed to result from destabilization of Hb by the binding of a ligand derived from the aryl portion of PHZ (13). Exposure of erythrocytes to PHZ results in the degradation of both monomers of spectrin, a major cytoskeleton membrane protein (27). These...