Currently, most physicians adopt a “restrictive” strategy of blood transfusion (transfuse when hemoglobin level < 7 g/dL) as recommended, except in acute hemorrhage or in patients with acute myocardial ischemia where a more liberal strategy is the usual practice [26]. Still, our study is...
Furthermore, as clinical experience and the knowledge base grows, it will become increasingly possible to develop more effective therapies. The field remains exciting and rele- vant. Even with a better appreciation of when to transfuse a patient, the options of what to use remain few. The ...
At the Consensus Conference (1988) it was also agreed that the decision to transfuse red blood cells in a specific patient should take into consideration the many factors that comprise clinical judgment. These factors include the duration ofanemia, the intravascular volume, the extent of surgery, ...
The effect was accentuated during daytime, weekday, and May–June months, persisted in analyses including all transfusions, and was absent at control thresholds.#Leading digit bias might have a modest influence on the decision to transfuse red cells. The findings may inform practice guidelines and...
and myelodysplastic syndrome. Due to local specificity, no other conditions were mentioned that could require higher RBC transfusion triggers, such as thalassemia or sickle cell disease. Nevertheless, if the decision was made to transfuse RBCs at a higher than recommended Hb concentration, there was...
It is formed when hemoglobin iron is oxidized from Fe2+ to Fe3+. Methemoglobin cannot bind O2!!! How can an animal have methemoglobinemia (2 main) Hereditary (rare) Acquired Acquired methemoglobinemia Exposure to exogenous oxidizing substances: garlic...
It is not always practical to transfuse a patient with donated blood. In these situations, use of a red blood cell substitute is desirable. The product must effectively transport O2, just as do red blood cells. ("Plasma expanders", such as dextran and albumin, do not transport oxygen.) ...
Diagnosis is by demonstration of a hemolytic anemia, detection of Heinz bodies (by staining), and the heat precipitation test. Hemoglobin electrophoresis is not always useful because of the tendency of the hemoglobin to rapidly denature. One should avoid oxidant drugs, transfuse as clinically indicate...
It is important, however, to consider the possible pitfalls associated with each device when making a clinical decision to transfuse. Copyright 2017 Elsevier Inc. All rights reserved.doi:10.1053/j.jvca.2017.11.022Kolotiniuk, Nikolai V.Manecke, Gerald R....