Anemia is the most widespread hematological disease, therefore the search for new approaches to erythropoiesis regulation in the body remains an extremely urgent problem. We studied the effect of long-term reduction of deuterium level in the internal milieu of the body on hemoglobin production and ...
An iron-containing protein in the blood of many animals that, in vertebrates, carries oxygen from the lungs to the tissues of the body and carries carbon dioxide from the tissues to the lungs. Hemoglobin is contained in the red blood cells of vertebrates and gives these cells their characteris...
Hemoglobin is contained within red blood cells and is essential for transporting oxygen around the body. Problems with hemoglobin production cause common diseases, such as anaemia, which comes from low levels of hemoglobin and is found in 25% of the world's population. "This new finding is crit...
This process also produces one molecule of carbon monoxide for every molecule of heme degraded [4]; this is one of the few natural sources of carbon monoxide production in the human body, and is responsible for the normal blood levels of carbon monoxide even in people breathing pure air. ...
However, under physiological conditions, the presence of free hemoglobin and heme due to a low level of RBC lysis in the body induces the production of specific scavenger proteins that help to neutralize them [15]. One such scavenger protein is haptoglobin (Hp), which binds to free hemoglobin...
much erythropoietin (a type of hormone that stimulates the production of red blood cells). Hormones are natural chemicals produced by the body and released into the blood that have a specific effect on tissues in the body. High hemoglobin levels can be caused by polycythemia vera. Polycythemia ...
The effect ofα-amino-/V-butyric acid (αABA) onfetal hemoglobinproduction in the adult was examined in vivo after being administered to normal and anemic baboons and in erythroidprogenitor cell cultures. Infusion of αABA for five days resulted in four- to fivefold increases in the level of...
Defects in HBA1 are the cause of alpha-thalassemia (A-THAL) [MIM:604131]. The thalassemias are the most common monogenic diseases and occur mostly in Mediterranean and Southeast Asian populations. The hallmark of alpha-thalassemia is an imbalance in globin-chain production in the adult HbA mole...
What organ in the body regulates erythrocyte production? What is the structure of myoglobin? How many heart valves in the human body? The body is at its lowest level of functioning during What does vitamin B9 do for the human body? What organ filters blood? What part of the body makes re...
4. Then the hBKLF expression level, proliferation ability, colony formation and hemoglobin production were detected by RT-PCR and Western blot, MTT method, methyl cellulose semisolid culture method and benzidine test respectively. 构建hBKLF正义及反义真核表达载体,转染K562细胞,经G418筛选4周,得到稳定...