The iron contained in hemoglobin is also responsible for the red color of blood. It also plays an important role in maintaining the shape of the red blood cells. In their natural shape, red blood cells are round with narrow centers resembling a donut without a hole in the middle. Abnormal...
With the exception of embryonic hemoglobins present in early fetal life, hemoglobin is a tetrameric protein consisting of two alpha (α) and two nonalpha polypeptide chains attached to four iron-containing heme complexes. All normal hemoglobins of adult life contain two α chains, with different...
The namehemoglobinis the concatenation ofhemeand globin, reflecting the fact that eachsubunitof hemoglobin is aglobular proteinwith an embeddedheme(or haem) group; each heme group contains an iron atom, and this is responsible for the binding of oxygen through ion-induced dipole forces. The most...
The iron contained in hemoglobin is also responsible for the red color of blood. It also plays an important role in maintaining the shape of the red blood cells. In their natural shape, red blood cells are round with narrow centers resembling a donut without a hole in the middle. Abnormal...
Methemoglobin (MetHb) is a hemoglobin (Hb) derivative with the heme iron in ferric state (Fe3+), unable to deliver oxygen. Quantification of methemoglobin is a very important diagnostic parameter in hypoxia. Recently, novel hemoglobin microparticles (Hb-MP) with a narrow size distribution around...
Hemoglobin is an iron-rich protein found in Red Blood Cells (RBC), giving them their unique red color. It is primarily responsible for carrying oxygen from your lungs to the tissues and organs of your body. A hemoglobin test is often used to detect anemia, which is a deficiency of RBC ...
Hemoglobin is the oxygen carrier in blood erythrocytes. Oxygen coordination is mediated by α2β2 tetrameric structure via binding of the ligand to the heme iron atom. This structure is essential for hemoglobin function in the blood. In the last few years, expression of hemoglobin has been foun...
Ferrous hemoglobin is easily converted into other forms of hemoglobin, such as methemoglobin (metHb)(hemoglobin in which divalent iron is oxidized to trivalent iron), and CO is combined to form carboxyhemoglobin (COHb), Combine with sulfide to form hemoglobin sulfide (SHb) and so on. What ...
Each globulin chain contains an iron ion embedded in a porphyrin molecule called heme, which directly binds the oxygen molecule and which is also responsible for the red color of blood. The heme also specifically interacts with the two other gases, carbon monoxide (CO) and nitric oxide (NO),...
The human serum protein, haptoglobin, forms a stable, irreversible complex with hemoglobin. Haptoglobin is composed of two H chains, which are connected via two smaller L chains to give a protein of 85,000 M r. In the complex, each H chain binds an αβ dimer of hemoglobin for a total...