The loss of two of the four genes is referred to as α-thalassemia trait. The pair of deleted genes may be from the same chromosome, or one α-globin gene may be deleted from each of the two chromosomes. The former situation is more common in Asian populations, whereas the latter is ...
All forms of SCD, as well as sickle trait, result in a positive sickle solubility test; therefore this procedure will not discriminate among these disorders. The Hb S mutation can also be detected by molecular methods. Differential Diagnosis The differential diagnosis of SCD includes other form...
when it became easy to detect sickle cell trait by simple hemoglobin electrophoresis, many African Americans refused to be tested out of fear that the information would be used against them. There were, in fact, some examples where employment discrimination followed identification of the trait. This...
In the late 1950s, when it became easy to detect sickle cell trait by simple hemoglobin electrophoresis, many African Americans refused to be tested out of fear that the information would be used against them. There were, in fact, some examples where employment discrimination followed ...
The members of this family with hemoglobin I trait have no other obvious clinical abnormalities. There has been no history of chronic illnesses or malformations in this family as far as the investigators have been able to find out. Electrophoresis of hemoglobin A/I (obtained from the father, II...
A sTfR value of N4.u8t9rienmtsg2/0L17h, 9a,d450a sensitivity of 86.8% and a specificity of 81.7%. Although there is no signifi5caofn9t difference in the areas under curves (AUC) for these indexes except for Hb, CHr still showed a slender superiority (Figure 2). difference in the...