Objective: To evaluate the hemoglobin threshold for red cell transfusion in children admitted to a pediatric intensive care unit (PICU). Methods: Retrospective chart review study. Tertiary care PICU. Critically ill pediatric patients requiring blood transfusion. No intervention. Results: We analyzed the...
However, transfusion of red blood cells (RBC) may cause adverse effects and increase cost. The authors hypothesized that the restrictive hemoglobin threshold (Hb of 80 g/L) may aggravate bleeding more than the higher Hb threshold (Hb 100 g/L).Laine, AnttiNiemi, TomiSchramko, Alexey...
increasing evidence suggests that a threshold of 7 g/dL is reasonably safe. However, in the post-CPB period, patients with incompleterevascularizationor with poor target vessels may require a higher transfusion threshold. As a result,blood transfusionsshould be individualized for each patient but sho...
A significant progression in this field had been achieved in cases of septic shock, mainly due to a recent large, multicenter, randomized study that compared a hemoglobin level threshold of 9 g/dL vs. 7 g/dL for blood transfusion in patients with septic shock in the ICU and found no ...
However, an increasing number of publications suggest there is no absolute threshold for transfusion, and that this decision should be based on an assessment of the overall clinical picture presented by the patient. This article reviews the risks associated with blood transfusions, and the data in...
Hemoglobin levels and transfusions in neurocritically ill patients: a systematic review of comparative studies Introduction Accumulating evidence suggests that, in critically ill patients, a lower hemoglobin transfusion threshold is safe. However, the optimal hemogl... P Desjardins,AF Turgeon,MH Tremblay...
Red blood cell transfusion thresholds in pediatric patients with sepsis. Furthermore, a restrictive transfusion threshold significantly reduced exposure to blood products. Our data suggest that a hemoglobin level of 7.0 g/dL may ... Oliver,Karam,Marisa,... - Pediatric critical care medicine : a ...
Hemoglobin levels and transfusions in neurocritically ill patients: a systematic review of comparative studies Introduction Accumulating evidence suggests that, in critically ill patients, a lower hemoglobin transfusion threshold is safe. However, the optimal hemogl... P Desjardins,AF Turgeon,MH Tremblay...
Hemolysis is associated with increased mortality in patients with sepsis, ARDS, or therapy with extracorporeal membrane oxygenation (ECMO). To quantify a critical threshold of hemolysis in patients with ARDS and treatment with veno-venous ECMO, we aimed
DRUG INTERACTIONS. ADLYXIN delays gastric emptying which may impact absorption of concomitantly administered oral medications. Oral medications that are particularly dependent onthreshold concentrations for efficacy, such as antibiotics, or medications for which a delay in effect isundesirable, such asacetamin...