Define Familial hemochromatosis. Familial hemochromatosis synonyms, Familial hemochromatosis pronunciation, Familial hemochromatosis translation, English dictionary definition of Familial hemochromatosis. or n pathol a hereditary disease that causes the
Synonyms Bronzed diabetes; iron storage disease Definition Hemochromatosis is a metabolic disorder in which excessive amounts of iron accumulate in the body, leading to tissue damage. It is to be distinguished from hemosiderosis in which excess iron may be present in tissues, but without tissue dama...
definition of penetrance and lack of comparison with matched controls in older studies.28 Prevalence of the clinical manifestations of HH-HFE such as joint pain, arthritis, skin pigmentation, and infertility have recently been found to be similar among screened p.C282Y homozygotes compared with the...
and hepatic and spleen iron overload mainly in Kupffer cells and macrophages (because of 'loss of function' variants) reflected by hyperferritinemia with high/normal or low TS.25 This disease requires a more careful differential diagnosis with other very common causes of hyperferritinemia such as...
By definition, participants without C282Y or H63D had HFE wt/wt. We linked 20,306 Canadian participants to the Ontario Death Registry for dates and causes of death 9 y after IS. We computed Cox proportional hazards to identify factors with increased death risks and Kaplan-Meier curves to ...
The term “restrictive cardiomyopathy” (RCM) includes a wide range of diseases that vary in etiology and pathogenesis. The main common feature of these various conditions is marked diastolic dysfunction. The current RCM definition is more descriptive rather than categorical. According to the Cardiomyop...
Read about the ECG test, interpretation, results, definition, and more. Ferritin Blood Test Ferritin is a protein in the body that is used to store iron. The ferritin blood test can detect elevated or low levels of ferritin in the body, which may indicate disease such as hemochromatosis, ...
Define Hereditary hemochromatosis. Hereditary hemochromatosis synonyms, Hereditary hemochromatosis pronunciation, Hereditary hemochromatosis translation, English dictionary definition of Hereditary hemochromatosis. or n pathol a hereditary disease that c