At Hematology & Oncology Consultants, P.C., we are dedicated to providing you with the best possible medical treatment by caring, compassionate physicians and staff who take a multidisciplinary approach to your care. Being diagnosed with cancer or a blood disorder can be extremely overwhelming. Our...
RAS isoform mutations exhibit selectivity across various cancers. Specifically, KRAS mutations are most commonly found in solid tumors, particularly in PDAC, CRC, lung adenocarcinoma (LUAD), uterine corpus endometrial carcinoma (UCEC), stomach adenocarcinoma (STAD), and testicular germ cell tumors (TGC...
The combination of venetoclax/ibrutinib/obinutuzumab is currently undergoing evaluation in the OASIS study that is enrolling both relapsed/refractory and newly diagnosed MCL. Preliminary results of the newly diagnosed cohort (n= 15) have recently been reported [85]. Venetoclax was given at 400 mg ...
NK cells are able to recognize and kill “stressed cells” including cells infected with viruses, allogeneic cells, and tumor cells without prior sensitization in a non-HLA (human leukocyte antigen)-restricted manner. The effector functions in NK cells are regulated through a balance of signals de...