It never fails to get the adrenaline going when you are the first one to see a CBC with a WBC of 400,000, a differential that is over 90% blasts, rare lymphoma cells, malarial parasites, or a body fluid smear full of malignant cells. The following 2 cases are a very remarkable looki...
We advise you to read our policy on conflict of interest statements, funding source declarations, author agreements/declarations and permission notes. Funding sources Authors must disclose any funding sources who provided financial support for the conduct of the research and/or preparation of the arti...
Notes Your contacts HORIBA Medical DISTRIBUTORS NETWORK Parc Euromédecine Rue du Caducée - BP 7290 34184 Montpellier Cedex 4 FRANCE Tel: (33) 4 67 14 15 16 Fax: (33) 4 67 14 15 17 HORIBA Medical online : http://www.horiba.com/medical HORIBA ABX SAS - SOCIÉTÉ PAR ACTIONS ...
Full size table In the realm of cell-based vaccines, various advancements have contributed to enhancing their efficacy. Whole-cell vaccines, employing a straightforward approach to target a broad array of CTL and T helper cell epitopes, have demonstrated low immunogenicity thus far. The addition of...
Glofit is a full-length IgG1 bsAb with a 2:1 molecular configuration of anti-CD20 and anti-CD3 (Table 1). The Fc of Glofit has a PG LALA mutation, resulting in the loss of the Fc-FcγRs interaction while retaining its binding ability to FcRn [1]. This particular structure possesses...
Author notes Miao Yu and Ke Sui have contributed equally. Authors and Affiliations Medical Center of Hematology; State Key Laboratory of Trauma and Chemical Poisoning;Chongqing Key Laboratory of Hematology and Microenvironment, Xinqiao Hospital of Army Medical University, Chongqing, 400037, China ...
A total of 312 full-text articles were assessed for eligibility. Data Extraction and Synthesis Data extraction and risk of bias assessments were performed according to the Preferred Reporting Items of Systematic Reviews and Meta-analyses (PRISMA) and Cochrane recommendations, and the quality of ...
Full size table 11.1% (8/72) patients experienced TRAEs leading to study drug discontinuation, most occurred in the tunlametinib 12 mg BID plus vemurafenib 960 mg BID and tunlametinib 15 mg BID plus vemurafenib 960 mg BID dose groups (Supplementary Table S3, online only). The most common ...
Please see accompanying fullprescribing informationfor Soliris, including Boxed WARNING regarding serious meningococcal infections. Notes CALQUENCE CALQUENCE (acalabrutinib) is a next-generation, selective inhibitor of Bruton’s tyrosine kinase (BTK). CALQUENCE binds covalently to BTK, thereby ...
Full size image Our results illustrate that patients diagnosed with COVID-19 after B-cell-targeted CAR-T-cell therapy have a very poor outcome. The COVID-19 attributable mortality rate of 41% is at least 4 but mostly 10–40 times higher than reported in the general population of countries...