Thus the affinity of the inhibitor towards [ES] was ~5-fold higher compared to [E] suggesting its preference to [ES]. The removal of TF did not alter its inhibitory mech- anism (Fig. 4D). However, Ki' for [ES] complex (FVIIa/FX/phospholipids) dropped ~3-fold to 103 ±...
In the second-generation mice, the percentage of GFP+ cells was maintained at a higher level in the DNMT3A-R882H group but dropped rapidly in the WT group (Fig.1D). At 1 y after BMT, remarkable differences of GFP+ cells appeared among the three groups: PB cells carrying DNMT3A- R...
We observed an average academic delay of 0.98聽years among the 59 subjects by Year 10 of secondary school (French class Troisi猫me), which was higher than the 0.34-year delay in the normal population ( P < .001) but not significantly higher than the delay of 0.68聽years in our cohort ...