Immunology Type I interferon inflames the helper T cell response UNIVERSITY OF WASHINGTON Murali-Krishna Kaja Havenar-DaughtonColinVaccine development is a major focus in the fight against human infectious diseases. Successful vaccines rely on the appropriate activation of T and B cells to form ...
Aronica MA, McCarthy S, Swaidani S, Mitchell D, Goral M, Sheller JR, Boothby M: Recall helper T cell response: t helper 1 cell-resistant allergic susceptibility without biasing uncommitted CD4 T cells. Am J Respir Crit Care Med 2004, 169:587-595...
Supernatants of DC-T cell cocultures were assayed by ELISA for IL-5 and IFN-γ. Results: A TH1-type response developed in purified CD4+ T cells from healthy donors in response to Der p 1–pulsed DCs, as indicated by high levels of IFN-γ in culture supernatants. In contrast, CD4+ T...
: a T cell that participates in an immune response by recognizing a foreign antigen and secreting lymphokines to activate T cell and B cell proliferation, that usually carries CD4 molecular markers on its cell surface, and that is reduced to 20 percent or less of normal numbers in AIDS ...
: a T cell that participates in an immune response by recognizing a foreign antigen and secreting lymphokines to activate T cell and B cell proliferation, that usually carries CD4 molecular markers on its cell surface, and that is reduced to 20 percent or less of normal numbers in AIDS ...
Head and neck squamous cell carcinoma (HNSCC) is a major cause of cancer-related morbidity and mortality worldwide. Epidermal growth factor receptor (EGFR)-targeted therapy is an attractive strategy alternative to conventional cancer treatments for HNSCC
The role of H-2-linked genes in helper T cell function. VII. Expression of I region and immune response genes by B cells in bystander help assays. 1980. The role of H-2-1inked genes in helper T cell function. VII. Expression of I region and immune response genes by B cells in ...
activation-induced cell death Th1: type 1 helper T cell Th2: type 2 helper T cell ThGM: GM-CSF-secreting helper T cell Tc1: type 1 cytotoxic T cell Tc2: type 2 cytotoxic T cell References Romagnani S . Regulation of the T cell response. Clin Exp Allergy 2006; 36: 1357–...
HelperT cellsare required for the generation of a potent immune response to foreign antigens. Amongst them, T follicular helper (Tfh) cells are specialized in promoting protective, long-livedantibody responsesthat arise fromgerminal centers. Within these structures, the specificity ofB cell receptorsma...
Helper T cells constitute a specific subpopulation of CD4+ T cells that provide help to other cells of the immune system in mounting an immune response through either direct cell–cell interaction or the secretion of cytokines. From: Reference Module in Neuroscience and Biobehavioral Psychology, 2017...