Hec1-overexpressing molecular subtypes of human lung cancer were identified. Conclusions The excellent potency, safety and synergistic profiles of this potent first-in-class Hec1-targeted small molecule TAI-1 show its potential for clinically utility in anti-cancer treatment regimens.doi:10.1186/1756-...
英文名称:Anti-HEC1别名:HEC 1; HEC; Highly Expressed in Cancer; Highly expressed in cancer protein; Highly express包装号:G320 产地:中国大陆/进口产品 商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology供应商:田源试剂 TR、新试剂 NR--- 产品详细描述产品介绍:Acts as a component of the ess...
Name: Anti-HEC1 Antibody See all HEC1 primary antibodiesDescription: Rabbit polyclonal antibody to HEC1 Specificity: HEC1 pAb detects endogenous levels of HEC1 protein. Applications: WB, IF Reactivity: Human, Mouse, Rat Immunogen: Synthetic peptide, corresponding to the 388-433 of Human HEC1....
3 Moreover, overexpression of cyclin E inducing multipolar divisions and numerous chromosome segregation errors was found to have a significant anti-tumorigenic effect in a mouse model for lung cancer.4 Consequently, the idea of promoting cell death by inducing massive chromosome mis-segregation at ...
Highly expressed in cancer protein 1 (Hec1) is a subunit of the kinetochore (KT)-associated Ndc80 complex, which ensures proper segregation of sister chromatids at mitosis by mediating the interaction between KTs and microtubules (MTs). HEC1 mRNA and protein are highly expressed in many maligna...
Cells were immunostained with tubulin DM1α antibodies and anti-GFP antibodies (Sigma). Acknowledgments We thank Dr. A. Khodjakov for PA-GFP-tubulin-expressing PtK1 cells and Dr. J. Tirnauer for GFP-EB1-expressing PtK1 cells. We thank the following for antibodies: Dr. P.T. Stukenberg,...
Robert F. Kennedy Jr. says he won't collect fees from litigation against the drugmakers of a cervical cancer vaccine if he's confirmed as the nation’s health secretary.
1、FDA Grants Priority Review to Trastuzumab Deruxtecan for Select HER2+ Metastatic Breast Cancer 2、Enhertu granted Priority Review in the US for patients with HER2-positive metastatic breast cancer treated with a prior anti-HER2-based...
Prediction and diagnosis of bone metastases in well-differentiated gastro-entero-pancreatic endocrine cancer: a prospective comparison of whole body magnet... Our purpose was to compare the sensitivity of whole body (WB) magnetic resonance imaging (MRI) and somatostatin receptor scintigraphy (SRS) for...
I’ve seen young men suffering from mental illnessunable to ask for help for fear it would make him less of a man.In fact inthe UK suicide is the biggest killer of men between 20-49; eclipsing roadaccidents, cancer and coronary heart disease. I’ve seen men made fragile andinsecure by...