Only HEB is co-bound with SUZ12 and JARID2 near to the TSS in ESCs (ESC_HEB/PRC2; green dotted box), but in ME, newly made HEB/ SMAD2/3 elements are shown near to the TSS as well as a distal region (ME_HEB/SMAD2/3; red dotted boxes). (f–h) Scatterplots comparing RNA-...