Blood must continuously be moved around the body, collecting and supplying vital substances to cells as well as removing waste from them. The heart acts as a pump using a combination ofsystole (contractions)anddiastole (relaxation)of the chambers. The cycle takes place in the following sequence....
Italy * Correspondence: michele.miragoli@unipr.it Received: 31 May 2017; Accepted: 4 July 2017; Published: 10 July 2017 Abstract: The heart consists of millions of cells, namely cardiomyocytes, which are highly organized in terms of structure and function, at both macroscale and microscale leve...