Carvedilol is a non-selective beta-adrenergic blocking drug with vasodilatory properties that has been recently approved by the U.S. Food and Drug Administration for use in patients with NYHA functional class II or III heart failure. It was the only agent to produce a statistically significant ...
Carvedilol is a non-selective beta-adrenergic blocking drug with vasodilatory properties that has been recently approved by the U.S. Food and Drug Administration for use in patients with NYHA functional class II or III heart failure. It was the only agent to produce a statistically significant ...
Thus non-selective (e.g. propranolol) or modestly beta-1 selective (e.g. metoprolol, atenolol) are associated with metabolic disturbance, bronchospasm, epinephrine/hypertensive interaction (with cigarette-smoking or insulin-induced hypoglycaemia), while the possession of alpha-blocking activity (e.g....
Heart rate reduction in heart failure: ivabradine or beta blockers? HeartrateBetablockersHeartfailureVagalstimulationIvabradine, a selective I f current inhibitor, decreasing the heart rate in those with sinus rhythm, has been... Maya,Guglin - 《Heart Failure Reviews》 被引量: 5发表: 2013年 ...
Behavioural abnormalities and selective neuronal loss in HD transgenic mice expressing mutated full-length HD cDNA. Huntington disease (HD) is an adult-onset, autosomal dominant inherited human neurodegenerative disorder characterized by hyperkinetic involuntary movement... PH Reddy,M Williams,V Charles,....
OBJECTIVES This study analyzed the effect of the beta1-selective beta-blocker metoprolol succinate controlled release/extended release (CR/XL) once daily on mortality, hospitalizations and tolerability in patients with severe heart failure. BACKGROUND There continues to be resistance to the incorporation...
Beta-blockers are often added to ACE inhibitor regimens for people with chronic heart failure. The merits of initial therapy with beta-blockers remain uncertain.Willenheimer and colleagues compared the efficacy of beginning treatment with a beta-blocker (biso-prolol) or an ACE inhibitor (enalapril...
and prevent the onset of heart failure symptoms in patients with asymptomatic systolic dysfunction. Careful control of the dosage of beta-blockers can improve patient status by improving LV ejection fraction, increasing exercise tolerance, slowing HF progression, reducing the need for hospitalization, an...
Blood pressure lowering efficacy of beta‐1 selective beta blockers for primary hypertension Background Beta blockers are commonly used to treat hypertension. The blood pressure reading is the primary tool for physicians and patients to assess the ... W Gwk,HN Boyda,JM Wright - 《Cochrane Data...
beta-Blockers reduce mortality and morbidity in heart failure. Many of their benefits can be explained solely by heart rate reduction (HRR). We aimed to ve... Micha?,Maczewski,Urszula,... - 《Cardiovascular Research》 被引量: 106发表: 2008年 Heart rate reduction during exercise-induced myo...