FFR-CT是基于常规CCTA图像, FFRCT通过CT冠状动脉树的提取和分析,结合病变(斑块大小、分布与狭窄程度)、左室心肌质量、血压等综合参数,配合CFD数值计算, 实现对于冠脉狭窄病变处的FFR无创评价,而且不需要腺苷等药物的充血诱导[4, 5]。FFRCT不仅可提供三支冠脉的综合性FFR数据,还可以得出冠脉树任何部位的FFR数据。在美...
有些患者没有心外膜冠脉病变,也可存在心脏微循环功能障碍(如高血压病、高脂血症、糖尿病等心血管病危险因素)同样造成心肌血流量(myocardial blood flow,MBF,单位:ml/min·每克心肌)及冠脉血流储备(coronary flow reserve,CFR)减低,有时可诱发心肌缺血,产生严重临床后果。 近年来值得关注的是PET心肌灌注显像(myocardi...
然而FAME系列研究提示,FFR引导的PCI治疗多血管CAD在总试验人群中未能证明不低于CABG。 随着医疗技术的进步,经导管主动脉瓣植入(TAVI)和分数流量储备(FFR)引导下的冠状动脉介入治疗(PCI)为严重AS和CAD患者提供了一种可能的、创伤更小...
Sites and patients were categorised as pre or post CT FFR health technology introduction. Clinical outcomes (all-cause death, myocardial infarction, cardiovascular death, revascularization) and resource utilization (downstream cardiac tests) were assessed at 2 years from NHS digital health records. ...
Fractional Flow Reserve (FFR) Measurement Track 20: Artificial Intelligence in Cardiology Artificial intelligence holds great promise for transforming cardiology by enabling more accurate diagnosis, personalized treatment, proactive risk management, and efficient healthcare delivery. As AI continues to evolve ...
Coronary computed tomography (CT) angiography has advanced and is first line in suitable patients, due to high rule-out power and further qualification of the diagnosis by functional assessment using noninvasive nuclear or magnetic resonance technology or CT-based fractional flow reserve (FFR-CT). ...
Nuclear cardiology studies use noninvasive techniques to assess cardiac muscle blood flow, measure the pumping perform of the heart in addition as visualize the scale and site of a coronary failure. Among the techniques of nuclear medicine, heart muscle insertion imaging is that the foremost usually...
Pamela.Douglas(杜克大学):CONFIRM[注册]研究继续确立了CT[血管造影]作为胸痛诊断中的一个主要工具。DEFACTO试验表明非侵入FFR(fractional.flow.reserve)的“圣杯”将很快会获得,这将显著地转换非侵入检查模式,并且也会改变导管室患者的转诊。超声方面没有重量级试验,超声适用标准的改变也会改变治疗。
近年来,基于CCTA影像数据应用高级计算流体力学及深度学习等方法获得的冠状动脉CT血流储备分数(coronary CT angiography derived fractional flow reserve,CT-FFR)能在单次检查期间同时提供冠状动脉的解剖和生理学信息,成为临床研究和应用的新热点。CT-FFR不需要改变原有CCTA的数据采集方案,不需要使用药物辅助,不会增加辐射...
同样,DISCOVER-FLOW研究、DeFACTO研究和NXT研究等结果均证明CT-FFR与有创FFR值的一致性较高;另外,PLATFORM研究结果表明,使用CT-FFR筛查中危验前概率的胸痛患者,可明显减少患者行有创冠脉造影检查的几率,并且MACE发生率无统计学差异。 心脏磁共振是评价患者心脏结构和功能的“金标准”,心脏电影序列能反映心脏大小和室...