Healthy heart valves withstand these stresses by continuously maintaining, and adapting an intricate yet highly ordered connective tissue system within the valvular structures [1]. The predominant biomechanical function of the valve is attributed to a highly organized network of extracellular matrix (ECM)...
CCL2 is associated with the severity of heart failure, and was found to be expressed in high levels in early burn injury [43]., The timing of this expression coincides with the increased presence of myocytes [44]. In mice, serum CCL2 is found to be significantly higher on day 1 post-...