V-HeFT I and II initially suggested that enalapril was superior to ISDN-HYD therapy for improving survival in all heart failure patients (enalapril reduced mortality 28% more than the ISDN-HYD therapy) [27,28].
In theDAPA-HFtrial, treatment with the SGLT2 inhibitordapagliflozin(Farxiga, AstraZeneca) on top of standard HFrEF meds, compared with standard meds only, led to significantly improved risknot onlyfor its clinical composite primary endpoint, but for mortality and a slew of other meaningful secondary...
Meaning These findings suggest that patients with heart failure could be given the choice between BA or MEDS to ameliorate depression.Abstract Importance Heart failure (HF) affects more than 6 million adults in the US and more than 64 million adults worldwide, with 50% prevalence of depression....
-add on for pts already on defined doses of guideline meds still w/ HF s/s -take w/ food -no mortality benefit CI = BP <90/50, HR <60, SSS, heart block, hepatic impairement, pacemaker, pregnancy DI = CYP 3A4 Digoxin positive inotropic action on the heart --> inc contractility ...
heart failurehospitalizationmorbiditymortalityHeart failure (HF) is a major cause of morbidity and mortality in the United States, accounting for >1 million hospitalizations and costing 30 billion USD every year. The 90-day readmission rates for HF remain high at 40%. Efforts to bend the cost ...
Improveoverallfunctionalcapacityandqualityoflife Reducedyspneaandfatigue Control/minimizeedemaandfluidretention TherapeuticGoals: AtriskforconditionstheincreaseHFrisk(bothtypes): Hypertensivedisease,DM,sleepapneaandCAD AntirejectionmedsthatincreaseBP,renaldisease,riskDM ...
estimated annual mortality for diastolic heart failure Diastolic heart failure: 5 - 8%Age-matched controls: 1% Again, when do you use beta blockers and when do you not with heart failure? Use beta blocker for general heart failure.DO NOT USE FOR DECOMPENSATED HEART FAILURE 最好的學習方式。免...
The lack of efficacy of stem cell therapy for the treatment of heart failure may be caused by the cells being 'washed away' within a few hours when existing intra-coronary or intramyocardial delivery methods are used, according to Dr Richard Jabbour, who carried out the research at the Londo...
Antihypertensive meds 1.40 0.3381 0.0013 1.26 0.2278 0.033 Family history of heart attack 1.57 0.4522 <0.0001 1.38 0.3239 <0.001 ln (CAC + 1) NA NA NA 1.32 0.2743 <0.0001 Baseline survival at 10 yrs, S(10) 0.99963 0.99833 The p values are based on a standard Cox proportional hazards model...
(Patrick) "Like she took care of all my meds. Prior to the surgery, she wouldn't even know what meds I was on. But after that, she was the one who knew what med, and when there were changes". (Albert) After being stabilised medically, reactions varied among men. Groups discussed ...