The global burden of prostate cancer (PC) is substantial, ranking among the top five cancers for both incidence and mortality [1]. It is particularly common in developed Countries since, in addition to individual biological and genetic factors, environment and lifestyle impact the risk of developi...
In vitro results demonstrated specific therapeutic activity of engineered MSCs by killing prostate cancer cells more than that of non-PSA expressing breast cancer cell line. In concordance, they also observed significant reduction in tumor growth in mice bearing prostate cancer xenograft. Other ...
Novel MRI Technique Distinguishes Healthy Prostate Tissue From Cancer Using ZincNalleyCatlin
Radiomics-based machine learning classifiers have shown potential for detecting bone metastases (BM) and for evaluating BM response to radiotherapy (RT). However, current radiomics models require large datasets of images with expert-segmented 3D regions of interest (ROIs). Full ROI segmentation is tim...
High b Value (2,000 s/mm2) Diffusion-Weighted Magnetic Resonance Imaging in Prostate Cancer at 3 Tesla: Comparison with 1,000 s/mm2 for Tumor Conspicuity a... OBJECTIVE: The objective of our study was to investigate tumor conspicuity and the discrimination potential for tumor aggressiveness on...
Over time, different techniques have been developed to guide the surgery and to improve the surgical outcome like Intra-MRI which gives the surgeon an updated plan on the tumor’s location and its solid boundaries8. However, intra-MRI are resource intensive as they require 20–30 minutes ...
An MRI basically uses a magnetic field and radio waves to create high-resolution images of soft tissues like discs, nerves, and ligaments. This can easily identify abnormalities such as herniated discs, spinal tumors, or nerve compression with exceptional clarity. On the other hand, a CT scan ...
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and prostate gland can be viewed to detect lumps, tumors, and stones that may be causing urinary bleeding. If a digital rectal examination of the prostate reveals enlargement, an ultrasound test can provide contrasting tissue images revealing more information about the condition of the prostate. ...
M. Taxol induces bcl-2 phosphorylation and death of prostate cancer cells. Cancer Res. 56, 1253–1255 (1996). 4. Miller, K. et al. Paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancer. NEJM. 357, 2666–2676 (2007). 5. Zhou, J. et al. The anticancer ...