Study Design Spectral karyotyping analysis of head and neck cancer. Methods Two cell lines (MDA886 and MSK922) and one primary tumor in short-term culture were subjected to metaphase growth arrest with colcemide in their exponential growth phase and fixed onto glass slides. Painting probes for ...
Head and neck squamous cell carcinoma (HNSCC) undergoes stepwise progression from normal tissues to precancerous leukoplakia, primary HNSCC, and metastasized tumors. To delineate the heterogeneity of tumor cells and their interactions during the progression of HNSCC, we employ single-cell RNA-seq profi...
However, the findings of CRGA in RICTOR, PTCH1, NF1 and BRCA2 and the presence of high TMB in a subset of MyC cases encourages continued use of CGP to search for targeted and immunotherapies for this rare type of progressive head and neck cancer. 1298 Genomic Profiling of the Two ...
Neurological Imaging:MRI head and brain scan for hearing loss, MS, epilepsy, cause of headaches etc Musculoskeletal Imaging:Knee, Neck, Shoulder and Back MRI scan for muscle injuries, ligament damage, labral tears, sprains and joint problems etc ...
A recent study conducted by the Faculty of Medicine at The Chinese University of Hong Kong (CU Medicine) discovered a novel genetic biomarker which can predict the survival of head and neck cancer patients. There are over 0.7 million new head and neck sq
Background and Objectives Soft tissue sarcomas of the head and neck (STSHN) comprise a rare group of malignancies. Our objective is to determine the utility of soft tissue sarcoma staging systems within the head and neck, and to validate an individualized soft tissue sarcoma nomogram within head...
Squamous cell carcinoma of the head and neck (HNSCC) is the sixth most common type of cancer in the United States. The goal of this study was to evaluate the contribution of estrogens to the development of HNSCCs. Various cell lines derived from early- and late-stage head and neck lesions...
However, the findings of CRGA in RICTOR, PTCH1, NF1 and BRCA2 and the presence of high TMB in a subset of MyC cases encourages continued use of CGP to search for targeted and immunotherapies for this rare type of progressive head and neck cancer. 1298 Genomic Profiling of the Two ...
A correlation between high EphB4 expression and decreased overall survival rates in head and neck cancer patients has also been demonstrated15. In addition to playing a role in tumor growth, and metastasis, Eph/ephrins have also been reported to impart radioresistance to cancer cells16,17. Eph...
Beclin 1 contributes to tumor suppression by removing defective or damaged organelles and other cellular components; however, its activity can also stimulate cancer initiation and progression. In head and neck cancer, Beclin 1 overexpression promotes autophagy, which limits DNA damage and chromosomal ...