However, it causes substantial toxicity, such as severe cytopenia and cytarabine-encephalopathy. The efficacy of HD-AraC for the treatment of core-binding-factor (CBF) AML has been well established; however, whether or not HD-AraC is suitable for the treatment of non-CBF AML is unclear. More...
Addition of cytarabine to HD-MTX improved complete response rate (46% vs. 18%) and 3-year OS (46% vs. 32%)18. Another IELSG phase 2 trial showed that patients treated with methotrexate-cytarabine plus thiotepa and rituximab had higher complete remission rate than those treated with ...
After high-dose chemotherapy (carmustine, etoposide, cytarabine, and melphalan [BEAM protocol]) 58 patients with advanced Hodgkin's disease or high-grade ... N Schmitz,P Dreger,DC Linch,... - 《Lancet》 被引量: 1917发表: 1996年 Myelodysplastic syndrome after autologous bone marrow transplantati...
米托蒽醌(Mifoxantrone,Mx)是一种蒽醌类抗肿瘤药,杓细胞周期非特异性药物.阿糖胞苷 (Cytarabine,Ara-c)是一种嘧啶拮抗剂,为细胞周期特异性药物.二者联合治疗急性淋巴... 王艾君 - 全国肿瘤护理学术交流暨专题讲座会议 被引量: 0发表: 2007年 MxA方案治疗难治性急性非淋巴细胞白血病临床观察 MxA方案治疗难治性...
Clinical Analysis of 25 Patients with lymphoid malignancies treated with modified hyper-fractionated cyclophosphamide, vincristine, doxorubicin, and dexamethasone alternated with high-dose methotrexate and cytarabine[J]. Chin J Clin Oncol, 2012,39(3):166-169. DOI: 10.3969/j.issn.1000-8179.2012.03.012 ...
lumbar puncture --> if pos then tx with prophylactic intrathecal cytarabine (inject this into subarachnoid space!) tx for ALL 1) Induction - goal is remission-->CNS prophy, cranial radiation therapy 2) consolidation- secure remission 3) intensification - add new agents to overcome resistance ...
cytarabine hydroxycarbamide chlormethine endoxan mitomycin bleomycin camptothecin vinblastin vincristin 免疫调节药 immunomodulators immunosuppressive agents immunostimu-lanyts immunopotentiating drugs ciclosporin antilymphocyte globulin levamisole interferon thymosin...
Is it Safe to Administer High-Dose Methotrexate (HD-MTX) without Monitoring Mtx Levels? Experience with 100 Cycles 来自 国家科技图书文献中心 喜欢 0 阅读量: 6 作者:K Vaishnavi,D Bansal,A Trehan,R Jain,S Attri 年份: 2017 收藏 引用 批量引用 报错 分享 全部来源 求助全文 国家科技图书文献中心...
DI, delayed intensification; SR, standard risk; IR, intermediate risk; HR, high risk; SCT, hematopoietic stem cell transplantation; HD MTX, high-dose methotrexate; 6MP, 6-mercaptopurine; VCR, vincristine; AraC, cytarabine; Dexa, dexamethasone; pred, prednisolone; TIT, triple intrathecal treatment...
Using multivariate Cox regression analysis BEAM conditioning (carmustine, cytarabine, etoposide and melphalan) was predictive for favourable outcome, better disease-/progression-free survival and a significantly lower risk for relapse. The cumulative incidence of relapse was 30%, even for patients in ...